Assay Method Information | |
| ChEMBL_1500343 (CHEMBL3588654) |
Description: | Inhibition of IRAK4 in human THP1-XBlue cells assessed as suppression of TLR4 agonist LPS-induced activation of NF-kappaB preincubated for 1 hr followed by LPS challenge measured after 5 hrs by secreted embryonic alkaline phosphatase reporter gene assay |
Affinity data for this assay | |
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