| Assay Method Information | |
| | ChEMBL_1867397 (CHEMBL4368372) |
| Description: | Inhibition of GDP bound N terminal His-tagged KRAS G12C/C118A mutant (unknown origin) (1 to 169 residues) assessed as reduction in SOS-mediated guanine nucleotide exchange preincubated for 2 hrs followed by addition of SOS and GTP and measured after 1 hr by alphascreen assay |
| Affinity data for this assay | |
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