| Assay Method Information | |
| | ChEMBL_1696317 (CHEMBL4047207) |
| Description: | Inhibition of 150 nM recombinant human topoisomerase-2alpha catalytic activity expressed in Saccharomyces cerevisiae JEL1 harboring topoisomerase1 deletion mutant assessed as reduction in enzyme-mediated relaxed pBR322 DNA strand passage after 2 mins in presence of APP(NH)P by ethidium bromide staining based agarose gel electrophoresis |
| Affinity data for this assay | |
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