| Assay Method Information | |
| | hERG Inhibition Assay |
| Description: | A preclinical assay was used to determine whether drug candidates inhibit hERG by examining their ability to block the potassium tail currents in HEK293 cells stably transfected with hERG cDNA. Concentration-response curves for test compounds were generated and the maximum inhibition and IC50 value determined. |
| Affinity data for this assay | |
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