| Assay Method Information | |
| | Inhibition Assay |
| Description: | The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization (FP) methodology (Huang, W., et al., J. Biomol Screen, 2002, 7: 215). In particular, the compounds of the following examples had activity in reference assays by exhibiting the ability to inhibit the hydrolysis of the phosphosphate ester bond of a cyclic nucleotide. |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |