| Assay Method Information | |
| | ChEMBL_2250703 (CHEMBL5164913) |
| Description: | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated C57BL/6 mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion preincubated for 3 hrs with LPS and for 30 mins with compound prior to nigericin addition and measured after 30 mins by ELISA |
| Affinity data for this assay | |
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