| Assay Method Information | |
| | ChEMBL_2224861 (CHEMBL5138374) |
| Description: | Inhibition of NLRP3 inflammasome activation in LPS/nigericin-stimulated PMA-differentiated human THP-1 macrophages assessed as reduction in pyroptosis pretreated with LPS followed by compound treatment for 30 mins then stimulation with nigericin and measured after 3 hrs by MTT assay |
| Affinity data for this assay | |
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