| Assay Method Information | |
| | ChEMBL_2135936 (CHEMBL4845546) |
| Description: | Inhibition of GDP-loaded His-tagged KRAS G12C mutant (2 to 182 residues) (unknown origin) assessed as inhibition of SOS1-catalyzed nucleotide exchange preincubated for 1 hr followed by SOS1 addition measured after 1 hr by TR-FRET assay |
| Affinity data for this assay | |
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