| Assay Method Information | |
| | ChEMBL_2102480 (CHEMBL4810876) |
| Description: | Inhibition of biotinylated KRAS G12C mutant (unknown origin) assessed as inhibition of SOS-catalyzed nucleotide exchange preincubated for 60 mins followed by addition of human recombinant SOS protein and unlabeled GTP and measured after 60 mins by TR-FRET analysis |
| Affinity data for this assay | |
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