Assay Method Information

Assay Name:  ChEMBL_1902568 (CHEMBL4404790)
Description:  Stabilization of wild type human transthyretin expressed in Escherichia coli BL21(DE3) Star assessed as dissociation constant for TTR-amyloid beta (1 to 42) complex formation at 200 uM at 25 degC pre-incubated with transthyretin before amyloid beta (1 to 42) addition by ITC assay (Rvb = 0.94 +/- 0.04 microM)
Affinity data for this assay
 

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