| Assay Method Information | |
| | SERT In Vitro Binding Assay |
| Description: | Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by filtration with through GF/B filters. Radioactivity was measured in WALLAC 1409 DSA liquid scintillation counter. Radioligand-binding data were analyzed using iterative curve fitting routines (GraphPAD/Prism, version 3.0-San Diego, CA, USA). |
| Affinity data for this assay | |
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