Assay Method Information

Assay Name:  Receptor Binding Assay
Description:  Receptor binding is determined for the Compound of Example 1, using the compound of Formula A as a control. The following literature procedures are used, each of which reference is incorporated herein by reference in their entireties: 5-HT2A. Ki=IC50(1+L⁢/⁢KD)where L=concentration of radioligand in the assay, and KD=affinity of the radioligand for the receptor. A Scatchard plot is used to determine the KD.
Affinity data for this assay
 

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