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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM74657
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
UBE2N_HUMAN | UBE2N | BLU | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Human
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM74657
Synonyms:
N-2,1,3-benzothiadiazol-4-yl-5-methyl-3-phenyl-4-isoxazolecarboxamide | cid_974361 | SMR000078779 | MLS000065201 | N-(2,1,3-benzothiadiazol-4-yl)-5-methyl-3-phenyl-4-isoxazolecarboxamide | N-(2,1,3-benzothiadiazol-4-yl)-5-methyl-3-phenyl-1,2-oxazole-4-carboxamide | 5-methyl-3-phenyl-N-piazthiol-4-yl-isoxazole-4-carboxamide
Type:
Small organic molecule
Emp. Form.:
C17H12N4O2S
Mol. Mass.:
336.07
SMILES:
Cc1onc(c1C(=O)Nc1cccc2nsnc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: