Reaction Details  Report a problem with these data
Cell Reactant:
Caseinolytic protein C1 (ClpC1 NTD-D1)
Syringe Reactant:
BDBM213240
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2017-02-21
ΔG°:
-10.53±n/a (kcal/mole)
pH:
7.5000±0.0000
Temperature:
298.1500±0.0000 (K)
ΔH° :
-9.17±0.06 (kJ/mole)
ΔS° :
0±0 (kJ/mole-K)
Citation
 Vasudevan, D; Rao, SP; Noble, CG Structural basis of mycobacterial inhibition by cyclomarin A J Biol Chem 288:30883-91 (2013) [PubMed]  Article 
Cell React
Name:
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-493]
Synonyms:
CLPC1_MYCTU | clpC1 | Caseinolytic protein C1 (ClpC1 NTD-D1)
Type:
Protein
Mol. Mass.:
54272.48
Organism:
Mycobacterium tuberculosis
Description:
M. tuberculosis ClpC1 N-terminal domain D1 (1-493 aa)
Residue:
493
Sequence:
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTG
  
Syringe React
Name:
BDBM213240
Synonyms:
Cyclomarin A1 (CymA1)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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