Reaction Details  Report a problem with these data
Cell Reactant:
C-terminal-binding protein 2 (CtBP2)
Syringe Reactant:
BDBM154570
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2015-10-15
ΔG°:
-7.89±0 (kcal/mole)
pH:
8.5000±0.0000
Temperature:
293.1500±0.0000 (K)
ΔH° :
-10.02±0.07 (kJ/mole)
ΔS° :
-0.01±0 (kJ/mole-K)
Citation
 Hilbert, BJ; Morris, BL; Ellis, KC; Paulsen, JL; Schiffer, CA; Grossman, SR; Royer, WE Structure-guided design of a high affinity inhibitor to human CtBP. ACS Chem Biol 10:1118-27 (2015) [PubMed]  Article 
Cell React
Name:
C-terminal-binding protein 2
Synonyms:
CTBP2_HUMAN | CTBP2 | C-terminal-binding protein 2 (CtBP2) | C-terminal-binding protein 2
Type:
Protein
Mol. Mass.:
48948.33
Organism:
Human
Description:
P56545
Residue:
445
Sequence:
MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
  
Syringe React
Name:
BDBM154570
Synonyms:
2-Hydroxyimino-3-phenylpropanoic acid (HIPP)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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