Reaction Details  Report a problem with these data
Cell Reactant:
Lipoxygenase type I-B (LOX)
Syringe Reactant:
BDBM50381226
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2015-10-01
ΔG°:
-8.11±0 (kcal/mole)
pH:
8.0000±0.0000
Temperature:
298.1500±0.0000 (K)
ΔH° :
461.72±0 (kJ/mole)
ΔS° :
1.57±0 (kJ/mole-K)
Citation
 Tomy, MJ; Sharanya, CS; Dileep, KV; Prasanth, S; Sabu, A; Sadasivan, C; Haridas, M Derivatives form better lipoxygenase inhibitors than piperine: in vitro and in silico study. Chem Biol Drug Des 85:715-21 (2015) [PubMed]  Article
Cell React
Name:
Lipoxygenase type I-B (LOX)
Synonyms:
LOX2_SOYBN | LOX1.2 | LOX2
Type:
Protein
Mol. Mass.:
97147.48
Organism:
Soybean
Description:
n/a
Residue:
865
Sequence:
MFSVPGVSGILNRGGGHKIKGTVVLMRKNVLDFNSVADLTKGNVGGLIGTGLNVVGSTLDNLTAFLGRSVALQLISATKPLANGKGKVGKDTFLEGIIVSLPTLGAGESAFNIQFEWDESMGIPGAFYIKNYMQVEFYLKSLTLEDVPNQGTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAALVGYREEELKNLRGDGKGERKEHDRIYDYDVYNDLGNPDHGENFARPILGGSSTHPYPRRGRTGRYPTRKDQNSEKPGEVYVPRDENFGHLKSSDFLAYGIKSLSQYVLPAFESVFDLNFTPNEFDSFQDVRDLHEGGIKLPTEVISTIMPLPVVKELFRTDGEQVLKFPPPHVIQVSKSAWMTDEEFAREMVAGVNPCVIRGLQEFPPKSNLDPTIYGEQTSKITADALDLDGYTVDEALASRRLFMLDYHDVFMPYIRRINQTYAKAYATRTILFLRENGTLKPVAIELSLPHPAGDLSGAVSQVILPAKEGVESTIWLLAKAYVVVNDSCYHQLMSHWLNTHAVIEPFIIATNRHLSALHPIYKLLTPHYRDTMNINALARQSLINADGIIEKSFLPSKHSVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSAPHGLRLLIEDYPYAVDGLEIWAAIKTWVQEYVSLYYARDDDVKPDSELQQWWKEAVEKGHGDLKDKPWWPKLQTIEELVEICTIIIWTASALHAAVNFGQYPYGGFILNRPTSSRRLLPEKGTPEYEEMVKSHQKAYLRTITSKFQTLVDLSVIEILSRHASDEVYLGQRDNPHWTSDSKALQAFQKFGNKLKEIEEKLARKNNDQSLSNRLGPVQLPYTLLHPNSEGLTCRGIPNSISI
  
Syringe React
Name:
BDBM50381226
Synonyms:
PIPERIC ACID
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: