Reaction Details  Report a problem with these data
Cell Reactant:
Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Syringe Reactant:
BDBM50308984
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2012-09-18
ΔG°:
-7.66±0.19 (kcal/mole)
pH:
7.5000±0.0000
Temperature:
277.1500±0.0000 (K)
ΔH° :
-15.93±0.1 (kJ/mole)
ΔS° :
-0.03±0 (kJ/mole-K)
Citation
 Lee, SG; Haakenson, W; McCarter, JP; Williams, DJ; Hresko, MC; Jez, JM Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. J Biol Chem 286:38060-8 (2011) [PubMed]  Article 
Cell React
Name:
Phosphoethanolamine N-methyltransferase 1
Synonyms:
Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Type:
Enzyme
Mol. Mass.:
53531.36
Organism:
Caenorhabditis elegans
Description:
Q86NB3
Residue:
475
Sequence:
MSTDQQSSVEDQTVAMVNVRRANFKSFWDKYSDKPDTNSMMLNHSAEELESSDRADILASLPLLHNKDVVDIGAGIGRFTTVLAETARWVLSTDFIDSFIKKNQERNAHLGNINYQVGDAVGLKMESNSVDLVFTNWLMMYLSDEETVEFIFNCMRWLRSHGIVHLRESCSEPSTGRSKAKSMHDTANANPTHYRFSSLYINLLRAIRYRDVDNKLWRFNVQWSCSVPTYIKRSNNWRQVHWLAEKVPAEDGAKGTSFNELVELIKNTWQNEQEAWDAKLDDEKYVWTDKVFSSALTSLPSNSTFFLYTPRTVSPYCHINAHTLAETFNANVWNTEIIPEYYRTSLTKSNNLKDQRVRFGWNQSLTDSVTYWQQKDALFDVFVATEFLSTVDDETIRQLPNVMSDGAKFITLEPVDEVNEAEMKQRIQELGYTLKSFTDVTDQCIEAQEQYFKDHEQLRDEKVIRKNWVLLELTH
  
Syringe React
Name:
BDBM50308984
Synonyms:
AdoCys | CHEMBL597532 | S-Adenosylhomocysteine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: