Compile Data Set for Download or QSAR
Report error Found 132 Enz. Inhib. hit(s) with all data for entry = 10589
TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835(WO2022104348, Example 63 | (R)-7-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552835(WO2022104348, Example 63 | (R)-7-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552839((R)-3-Hydroxy-1-methyl-3-(3-(5-methyl-2-(5H-pyrrol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552838((R)-1-(3-(2-(1H-Pyrrolo[2,3-b]pyrldin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552841((R)-3-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552840((R) -3-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552845((R)-3-(4-(3-(3-Hydroxy-1-methyl-2-oxopyrrolidin-3-...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552846(WO2022104348, Example 73 | (R)-3-Hydroxy-1-methyl-...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552813(WO2022104348, Example 40 | (R)-3-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552823((R)-3-Hydroxy-3-(3-(5-(hydroxymethyl)-2-(1H-pyrrol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552822((R)-3-Hydroxy-3-(3-(2-(5-methoxy-1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552824((R)-3-(4-(3-(3-Hydroxy-1-methyl-2-oxopyrrolidin-3-...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552827((R)-3-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552826((R)-3-(3-(2-(7H-Pyrrolo[2,3-b]pyrimidin-5-yl)thiaz...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552832((R)-4-(3-(4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552867((R)-3-(3-(2-(4,5-Difluoro-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552866((R)-3-(3-(5-(1H-Pyrrolo[2,3-b]pyridin-3-yl)furan-3...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552869((R)-7-(3-(2-(4,5-Difluora-1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552868((R)-3-(3-(2-(5-Chloro-4-fluoro-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552870((R)-7-(3-(2-(5-Chloro-4-fluoro-1H-pyrrolo[2,3-b]py...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552872((R)-3-(3-(5-Fluoro-2-(1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552854((R)-7-(3-(2-(2-Methyl-5H-pyrrolo[2,3-b]pyrazin-7-y...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552856((R)-7-(3-(2-(3-Methyl-5H-pyrrolo[2,3-b]pyrazin-7-y...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552861((R)-7-(3-(2-(7H-pyrrolo[2,3-c]pyridazin-5-yl)thiaz...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552860((R)-7-(3-(2-(4-Methyl-1H-pyrrolo[2,3-b]pyndin-3-yl...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552865((S)-3-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552899(WO2022104348, Example 126)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552900((R)-3-(3-(4-(1H-Pyrrolo[2,3-b]pyridin-4-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552775((R)-7-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552778((R)-7-(3-(2-(7H-Pyrrolo[2,3-b]pyrimidin-5-yl)thiaz...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552781((R)-3-(3-(4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552780((R)-3-Hydroxy-1-methyl-3-(3-(2-(5-methyl-1H-pyrrol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552783((R)-7-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552784((R)-7-(3-(4-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552882((R)-3-(3-(4-(1 /-/-Pyrrolo[2,3-b]pyridin-3-yl)-2H-...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552887(WO2022104348, Example 114)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552889((R)-3-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)oxazol-...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552895((R)-3-(3-(3-(1H-Pyrrolo[2,3-b]pyndin-3-yl)-1H-pyra...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552894((R)-3-(3-(3-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-1H-1 ,...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552803((R)-7-(3-(5-(1H-Pyrrolo[2,3-b]pyridin-3-yl)furan-3...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552802((R)-7-(3-(2-(4-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552805((R)-4-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552806((R)-7-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552809((R)-7-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552811((R)-8-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552813(WO2022104348, Example 40 | (R)-3-(3-(2-(5H-Pyrrolo...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552814((R)-7-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552786(WO2022104348, Example 19 | WO2022104348, Example 1...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552789((R)-3-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552784((R)-7-(3-(4-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol...)
Affinity DataIC50: 100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104348

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