Compile Data Set for Download or QSAR
Report error Found 144 Enz. Inhib. hit(s) with all data for entry = 10362
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530621(WO2022076495, EXAMPLE 65 | 1-(5-(difluoromethoxy)-...)
Affinity DataIC50: 0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530630(WO2022076495, EXAMPLE 70a)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530622(WO2022076495, EXAMPLE 66a)
Affinity DataIC50: 1.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530640(WO2022076495, EXAMPLE 75a)
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530624(WO2022076495, EXAMPLE 67a)
Affinity DataIC50: 1.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530556(WO2022076495, EXAMPLE 2 | 1-(3-(difluoromethoxy)ph...)
Affinity DataIC50: 1.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530627(WO2022076495, EXAMPLE 68b)
Affinity DataIC50: 1.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530648(WO2022076495, EXAMPLE 79 | 1-(5-(Difluoromethoxy)-...)
Affinity DataIC50: 2.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530557(WO2022076495, EXAMPLE 3)
Affinity DataIC50: 2.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530641(WO2022076495, EXAMPLE 75b)
Affinity DataIC50: 2.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530636(WO2022076495, EXAMPLE 73a)
Affinity DataIC50: 2.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530689(WO2022076495, EXAMPLE 120)
Affinity DataIC50: 3.20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530637(WO2022076495, EXAMPLE 73b)
Affinity DataIC50: 3.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530629(WO2022076495, EXAMPLE 69b)
Affinity DataIC50: 3.90nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530684(WO2022076495, EXAMPLE 115 | l-(2-(2,2-difluoroetho...)
Affinity DataIC50: 4.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530626(WO2022076495, EXAMPLE 68a)
Affinity DataIC50: 4.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530563(WO2022076495, EXAMPLE 9)
Affinity DataIC50: 4.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530633(WO2022076495, EXAMPLE 71b)
Affinity DataIC50: 5.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530687(WO2022076495, EXAMPLE 118)
Affinity DataIC50: 5.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530644(WO2022076495, EXAMPLE 77a)
Affinity DataIC50: 5.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530651(WO2022076495, EXAMPLE 82)
Affinity DataIC50: 5.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530638(WO2022076495, EXAMPLE 74a)
Affinity DataIC50: 6.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530650(WO2022076495, EXAMPLE 81)
Affinity DataIC50: 6.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530634(WO2022076495, EXAMPLE 72a)
Affinity DataIC50: 6.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530639(WO2022076495, EXAMPLE 74b)
Affinity DataIC50: 6.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530635(WO2022076495, EXAMPLE 72b)
Affinity DataIC50: 6.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530569(WO2022076495, EXAMPLE 15)
Affinity DataIC50: 6.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530679(WO2022076495, EXAMPLE 110)
Affinity DataIC50: 7nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530649(WO2022076495, EXAMPLE 80)
Affinity DataIC50: 7.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530643(WO2022076495, EXAMPLE 76b)
Affinity DataIC50: 7.90nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530558(WO2022076495, EXAMPLE 4 | 3-(3-(difluoromethoxy)ph...)
Affinity DataIC50: 8.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530678(WO2022076495, EXAMPLE 109)
Affinity DataIC50: 9nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530628(WO2022076495, EXAMPLE 69a)
Affinity DataIC50: 9.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530645(WO2022076495, EXAMPLE 77b)
Affinity DataIC50: 9.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530599(WO2022076495, EXAMPLE 45a)
Affinity DataIC50: 12nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530677(WO2022076495, EXAMPLE 108 | 1-[3-(difluoromethoxy)...)
Affinity DataIC50: 12nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530647(WO2022076495, EXAMPLE 78b)
Affinity DataIC50: 13nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530568(WO2022076495, EXAMPLE 14)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530565(WO2022076495, EXAMPLE 11)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530561(WO2022076495, EXAMPLE 7)
Affinity DataIC50: 16nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530567(WO2022076495, EXAMPLE 13)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530623(WO2022076495, EXAMPLE 66b)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530590(WO2022076495, EXAMPLE 36)
Affinity DataIC50: 19nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530656(WO2022076495, EXAMPLE 87 | l-isopropyl-A-(4-methyl...)
Affinity DataIC50: 20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530664(WO2022076495, EXAMPLE 95)
Affinity DataIC50: 23nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530579(WO2022076495, EXAMPLE 25 | 1-(3-(difluoromethoxy)p...)
Affinity DataIC50: 23nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530592(WO2022076495, EXAMPLE 38)
Affinity DataIC50: 24nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530662(WO2022076495, EXAMPLE 93)
Affinity DataIC50: 24nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530686(WO2022076495, EXAMPLE 117)
Affinity DataIC50: 27nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM530572(WO2022076495, EXAMPLE 18)
Affinity DataIC50: 28nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

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