Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 10358
LigandPNGBDBM530430(6-(6-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopro...)
Affinity DataIC50: 0.180nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530432(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 0.380nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530442(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 0.450nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530441(WO2022070068, Example 22 | (S*)-7-Fluoro-6-(5-(1-h...)
Affinity DataIC50: 0.480nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530444(2-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-7-fluoro-6-(...)
Affinity DataIC50: 0.510nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530439((R*)-7-Fluoro-6-(2-(1-hydroxyethyl)-1-methyl-1H-im...)
Affinity DataIC50: 0.510nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530432(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 0.540nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530435(7-Fluoro-6-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1...)
Affinity DataIC50: 0.570nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530435(7-Fluoro-6-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1...)
Affinity DataIC50: 0.640nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530445(2-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-7-fluoro-6-(...)
Affinity DataIC50: 0.710nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530438((S*)-7-Fluoro-6-(2-(1-hydroxyethyl)-1-methyl-1H-im...)
Affinity DataIC50: 0.730nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530433(Racemic 7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H...)
Affinity DataIC50: 1.10nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530441(WO2022070068, Example 22 | (S*)-7-Fluoro-6-(5-(1-h...)
Affinity DataIC50: 1.10nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530436(7-Fluoro-6-(2-(hydroxymethyl)-1-methyl-1H-imidazol...)
Affinity DataIC50: 1.20nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530454(7-Fluoro-6-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1...)
Affinity DataIC50: 1.20nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530453(7-Fluoro-6-(2-(2-hydroxypropan-2-yl)-1-methyl-1H-i...)
Affinity DataIC50: 1.20nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530455(2-(3-Chloro-6-methylpyridin-2-yl)-7-fluoro-6-(2-(2...)
Affinity DataIC50: 1.40nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530440((R*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,...)
Affinity DataIC50: 1.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530434(6-(5-Acetyl-1-methyl-1H-1,2,4-triazol-3-yl)-7-fluo...)
Affinity DataIC50: 1.70nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530446(2-(2-Chloro-4-methylpyridin-3-yl)-7-fluoro-6-(2-(2...)
Affinity DataIC50: 2nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530440((R*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,...)
Affinity DataIC50: 2nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530447(2-(2-Chloro-4-methylpyridin-3-yl)-7-fluoro-6-(5-(2...)
Affinity DataIC50: 2.5nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530437(7-Fluoro-6-(5-(hydroxymethyl)-1-methyl-1H-1,2,4-tr...)
Affinity DataIC50: 2.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530429(6-(5-Cyclopropylpyrazin-2-yl)-7-fluoro-4-isopropyl...)
Affinity DataIC50: 2.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530443((R*)-7-Fluoro-6-(5-(1-hydroxyethyl)-1-methyl-1H-1,...)
Affinity DataIC50: 2.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530431(6-(4-Amino-5-methylpyridin-2-yl)-7-fluoro-4-isopro...)
Affinity DataIC50: 3.60nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530452(6-(5-Acetyl-1-ethyl-1H-1,2,4-triazol-3-yl)-7-fluor...)
Affinity DataIC50: 6.20nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530456(6-(1-Ethyl-5-(1-hydroxyethyl)-1H-1,2,4-triazol-3-y...)
Affinity DataIC50: 19nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068

LigandPNGBDBM530448(6-(1-Ethyl-5-(2-hydroxypropan-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 27nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022070068