Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 3169
TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM393526(US9963456, Example Comp.)
Affinity DataIC50: 12nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321052(US10174040, Example 136 | [(1R,2R,3S,4R)-4-[4-Amin...)
Affinity DataIC50: 31nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321054(US10174040, Example 138 | [(1R,2S,4R)-4-[4-Amino-5...)
Affinity DataIC50: 120nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321024(4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...)
Affinity DataIC50: 180nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321065(US10174040, Example 126 | 4-[4-Amino-7-[(2R,4S,5R)...)
Affinity DataIC50: 260nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321044(4-Amino-5-[2-(2-ethoxy-6-fluoro-phenyl)ethynyl]-7-...)
Affinity DataIC50: 340nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320969(4-Amino-5-[2-(4-amino-2,6-difluoro-phenyl)ethynyl]...)
Affinity DataIC50: 400nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321055(US10174040, Example 139 | [(2R,3S,5R)-5-[4-Amino-5...)
Affinity DataIC50: 410nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320997(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 790nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321051(US10174040, Example 134 | [(2R,3S,5R)-5-[4-Amino-5...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321047(US10174040, Example 130 | 4-Amino-7-[(1R,4R,5S)-4,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321046(US10174040, Example 129 | 4-Amino-7-[(1R,4R,5S)-4,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320996(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321042(8-[2-[4-amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(s...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321040(4-Amino-5-[2-[2,6-difluoro-4-[(3R)-3-hydroxypyrrol...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321025(4-Amino-7-[(1R,2S,3R,4R)-2,3-dihydroxy-4-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321057(US10174040, Example 143 | 4-Amino-5-[2-(2-ethylsul...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321017(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321016(4-Amino-5-[2-[2-(cyclopropylmethoxy)-6-fluoro-phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321001(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321000(8-[2-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(s...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321063(US10174040, Example 36 | 4-Amino-7-[(2R,3R,4S,5R)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320957(4-[4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulf...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321059(US10174040, Example 3 | 4-Amino-5-[2-(4-benzyloxyp...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321060(US10174040, Example 6 | 4-Amino-7-[(2R,3R,4S,5R)-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320959(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321061(US10174040, Example 12 | 4-[4-Amino-7-[(2R,3R,4S,5...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321062(US10174040, Example 14 | 4-Amino-7-[(2R,3R,4S,5R)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320970(4-Amino-5-[2-[2,6-difluoro-4-(methylamino)phenyl]e...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320972(4-Amino-5-[2-[2,6-difluoro-4-[(3R)-3-fluoropyrroli...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320976(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320956(4-Amino-5-[2-(2,6-difluorophenyl)ethynyl]-7-[(2R,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320979(4-Amino-5-[2-[2,6-difluoro-4-(3-hydroxyazetidin-1-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320983(4-amino-5-[2-[4-(azetidin-1-yl)-2,6-difluoro-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320985(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent

TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320986(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320987(4-Amino-5-[2-(2-cyanophenyl)ethynyl]-7-[(2R,3R,4S,...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM321064(US10174040, Example 50 | 4-Amino-5-(3-cyclohexylpr...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320989(4-Amino-5-[2-(5-benzyloxy-2-pyridyl)ethynyl]-7-[(2...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
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TargetCarbonic anhydrase 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM320991(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The carbonic anhydrase II enzyme activity inhibition was measured by measuring the esterase activity in which carbonic anhydrase II degrades 4-nitrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2020
Entry Details
Go to US Patent