Compile Data Set for Download or QSAR
Report error Found 1937 Enz. Inhib. hit(s) with all data for entry = 2763
Target72 kDa type IV collagenase(Human)
Galapagos

US Patent
LigandPNGBDBM379774(US9926281, Compound 448 | US9926281, Compound 279)
Affinity DataIC50: 2nMAssay Description:MMP2: Protocol 2: The basis for the assay is the cleavage of the substrate 390 MMP FRET substrate I (Anaspec, Catalog n#: AS-27076) by human MMP2 (R&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379670(US9926281, Compound 194 | US9926281, Compound 413)
Affinity DataIC50: 5nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379686(US9926281, Compound 212)
Affinity DataIC50: 5nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetCollagenase 3(Human)
Galapagos

US Patent
LigandPNGBDBM379776(US9926281, Compound 234)
Affinity DataIC50: 5.60nMAssay Description:MMP-13:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP13 (Chemicon, Cat #CC06...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379668(US9926281, Compound 192 | US9926281, Compound 411)
Affinity DataIC50: 6nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379681(US9926281, Compound 416 | US9926281, Compound 207)
Affinity DataIC50: 6nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379653(US9926281, Compound 176)
Affinity DataIC50: 7nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379669(US9926281, Compound 193 | US9926281, Compound 412)
Affinity DataIC50: 7nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetMatrix metalloproteinase-14(Human)
Galapagos

US Patent
LigandPNGBDBM379776(US9926281, Compound 234)
Affinity DataIC50: 7nMAssay Description:MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetMatrix metalloproteinase-14(Human)
Galapagos

US Patent
LigandPNGBDBM379901(US9926281, Compound 396)
Affinity DataIC50: 7nMAssay Description:MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379645(US9926281, Compound 408 | US9926281, Compound 167)
Affinity DataIC50: 10nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379649(US9926281, Compound 172 | US9926281, Compound 409)
Affinity DataIC50: 11nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379667(US9926281, Compound 191)
Affinity DataIC50: 11nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379678(US9926281, Compound 204)
Affinity DataIC50: 11nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379668(US9926281, Compound 192 | US9926281, Compound 411)
Affinity DataIC50: 11nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379670(US9926281, Compound 194 | US9926281, Compound 413)
Affinity DataIC50: 11nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379668(US9926281, Compound 192 | US9926281, Compound 411)
Affinity DataIC50: 11nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379670(US9926281, Compound 194 | US9926281, Compound 413)
Affinity DataIC50: 11nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379681(US9926281, Compound 416 | US9926281, Compound 207)
Affinity DataIC50: 12nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379686(US9926281, Compound 212)
Affinity DataIC50: 12nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379681(US9926281, Compound 416 | US9926281, Compound 207)
Affinity DataIC50: 12nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379669(US9926281, Compound 193 | US9926281, Compound 412)
Affinity DataIC50: 13nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379764(US9926281, Compound 428 | US9926281, Compound 224)
Affinity DataIC50: 14nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379869(US9926281, Compound 455 | US9926281, Compound 331)
Affinity DataIC50: 14nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379869(US9926281, Compound 455 | US9926281, Compound 331)
Affinity DataIC50: 14nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379764(US9926281, Compound 428 | US9926281, Compound 224)
Affinity DataIC50: 14nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379666(US9926281, Compound 190)
Affinity DataIC50: 15nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379620(US9926281, Compound 121)
Affinity DataIC50: 15nMAssay Description:ADAMTS-5:Protocol 1: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379620(US9926281, Compound 121)
Affinity DataIC50: 15nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379780(US9926281, Compound 435 | US9926281, Compound 236)
Affinity DataIC50: 15nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379780(US9926281, Compound 435 | US9926281, Compound 236)
Affinity DataIC50: 15nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379678(US9926281, Compound 204)
Affinity DataIC50: 16nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379653(US9926281, Compound 176)
Affinity DataIC50: 16nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379778(US9926281, Compound 235)
Affinity DataIC50: 16nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379651(US9926281, Compound 174)
Affinity DataIC50: 17nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379692(US9926281, Compound 218)
Affinity DataIC50: 17nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379649(US9926281, Compound 172 | US9926281, Compound 409)
Affinity DataIC50: 17nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379797(US9926281, Compound 245 | US9926281, Compound 437)
Affinity DataIC50: 17nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

LigandPNGBDBM379649(US9926281, Compound 172 | US9926281, Compound 409)
Affinity DataIC50: 17nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379797(US9926281, Compound 245 | US9926281, Compound 437)
Affinity DataIC50: 17nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379689(US9926281, Compound 215)
Affinity DataIC50: 18nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetADAMTS5(Rat)
Galapagos

US Patent
LigandPNGBDBM379703(US9926281, Compound 405 | US9926281, Compound 422)
Affinity DataIC50: 18nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379760(US9926281, Compound 220 | US9926281, Compound 425)
Affinity DataIC50: 18nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379698(US9926281, Compound 265)
Affinity DataIC50: 18nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379872(US9926281, Compound 379)
Affinity DataIC50: 18nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379760(US9926281, Compound 220 | US9926281, Compound 425)
Affinity DataIC50: 18nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379645(US9926281, Compound 408 | US9926281, Compound 167)
Affinity DataIC50: 19nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379774(US9926281, Compound 448 | US9926281, Compound 279)
Affinity DataIC50: 19nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379829(US9926281, Compound 263)
Affinity DataIC50: 19nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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LigandPNGBDBM379831(US9926281, Compound 264)
Affinity DataIC50: 19nMAssay Description:ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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