Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 2784
TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380609(US9890124, 18 | 2-Amino-8-[3-[[(3S)-3-hydroxy-1-pi...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380604(US9890124, 13 | 2-Amino-8-[3-[(4-hydroxy-1-piperid...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380604(US9890124, 13 | 2-Amino-8-[3-[(4-hydroxy-1-piperid...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380605(US9890124, 14 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380605(US9890124, 14 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380606(US9890124, 15 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380606(US9890124, 15 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380607(US9890124, 16 | 2-Amino-8-[3-[3-(hydroxymethyl)aze...)
Affinity DataEC50:  2nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380607(US9890124, 16 | 2-Amino-8-[3-[3-(hydroxymethyl)aze...)
Affinity DataEC50:  2.60E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380608(US9890124, 17 | 2-Amino-8-[3-[[(3R)-3-hydroxy-1-pi...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380608(US9890124, 17 | 2-Amino-8-[3-[[(3R)-3-hydroxy-1-pi...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380609(US9890124, 18 | 2-Amino-8-[3-[[(3S)-3-hydroxy-1-pi...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380603(US9890124, 12 | 2-Amino-8-[3-(6-hydroxyhexylsulfam...)
Affinity DataEC50:  1.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380610(US9890124, 19 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  9nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380610(US9890124, 19 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  1.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(US9890124, 20 | 2-Amino-8-(5-piperazin-1-ylsulfony...)
Affinity DataEC50:  17nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380611(US9890124, 20 | 2-Amino-8-(5-piperazin-1-ylsulfony...)
Affinity DataEC50:  5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380612(US9890124, 21 | 2-Amino-8-(3-piperazin-1-ylsulfony...)
Affinity DataEC50:  18nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380612(US9890124, 21 | 2-Amino-8-(3-piperazin-1-ylsulfony...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380613(US9890124, 22 | 2-Amino-8-[5-(3-aminopyrrolidin-1-...)
Affinity DataEC50:  31nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380613(US9890124, 22 | 2-Amino-8-[5-(3-aminopyrrolidin-1-...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380614(US9890124, 23 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380614(US9890124, 23 | 2-Amino-8-[3-[(3R)-3-hydroxypyrrol...)
Affinity DataEC50:  1.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380598(US9890124, 7 | 2-Amino-8-[3-[(3R)-3-hydroxypyrroli...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380541(US9890124, 1 | 2-Amino-N,N-dipropyl-8-(3-sulfamoyl...)
Affinity DataEC50:  3.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380542(US9890124, 2 | 2-Amino-8-[3-(2-hydroxyethylsulfamo...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380542(US9890124, 2 | 2-Amino-8-[3-(2-hydroxyethylsulfamo...)
Affinity DataEC50:  7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380546(US9890124, 3 | 2-amino-N,N-dipropyl-8-(3-pyrrolidi...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380546(US9890124, 3 | 2-amino-N,N-dipropyl-8-(3-pyrrolidi...)
Affinity DataEC50: >1.00E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380584(US9890124, 4 | 2-Amino-N,N-dipropyl-8-(5-sulfamoyl...)
Affinity DataEC50:  23nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380584(US9890124, 4 | 2-Amino-N,N-dipropyl-8-(5-sulfamoyl...)
Affinity DataEC50:  5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380596(US9890124, 5 | 2-Amino-8-[3-(3-hydroxypyrrolidin-1...)
Affinity DataEC50:  3nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380596(US9890124, 5 | 2-Amino-8-[3-(3-hydroxypyrrolidin-1...)
Affinity DataEC50:  1.03E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380597(US9890124, 6 | 2-Amino-8-[4-(3-hydroxypyrrolidin-1...)
Affinity DataEC50:  10nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380597(US9890124, 6 | 2-Amino-8-[4-(3-hydroxypyrrolidin-1...)
Affinity DataEC50:  1.04E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380541(US9890124, 1 | 2-Amino-N,N-dipropyl-8-(3-sulfamoyl...)
Affinity DataEC50:  6nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380598(US9890124, 7 | 2-Amino-8-[3-[(3R)-3-hydroxypyrroli...)
Affinity DataEC50:  1.80E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380599(US9890124, 8 | 2-Amino-8-[3-[(3S)-3-hydroxypyrroli...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380599(US9890124, 8 | 2-Amino-8-[3-[(3S)-3-hydroxypyrroli...)
Affinity DataEC50:  2.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380600(US9890124, 9 | 2-Amino-8-[3-(3-hydroxyazetidin-1-y...)
Affinity DataEC50:  5nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380600(US9890124, 9 | 2-Amino-8-[3-(3-hydroxyazetidin-1-y...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380601(US9890124, 10 | 2-Amino-8-[3-[2-hydroxyethyl(methy...)
Affinity DataEC50:  4nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380601(US9890124, 10 | 2-Amino-8-[3-[2-hydroxyethyl(methy...)
Affinity DataEC50:  2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380602(US9890124, 11 | 2-Amino-8-[3-[2-(2-hydroxyethoxy)e...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380602(US9890124, 11 | 2-Amino-8-[3-[2-(2-hydroxyethoxy)e...)
Affinity DataEC50:  1.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM380603(US9890124, 12 | 2-Amino-8-[3-(6-hydroxyhexylsulfam...)
Affinity DataEC50:  8nMAssay Description:For TLR8 and TLR7 activity testing, HEK-Blue human TLR8 or TLR7 cells (Invivogen, San Diego, Calif., USA) are used, respectively. These cells are des...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2020
Entry Details
Go to US Patent