Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 2442
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285640(US10077272, Example 6 | 5-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  30.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285644(US10077272, Example 10 | 4,6-Dimethyl-5-[2-methyl-...)
Affinity DataKi:  32.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285640(US10077272, Example 6 | 5-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  40.2nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285640(US10077272, Example 6 | 5-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  44.7nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285647(US10077272, Example 13 | 5-[4-(furo[2,3-d]pyrimidi...)
Affinity DataKi:  70.3nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285655(US10077272, Example 21 | 1-cyclopropyl-6-[4-(furo[...)
Affinity DataKi:  122nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285637(US10077272, Example 3 | 6-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  127nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285656(US10077272, Example 22 | 1-cyclopropyl-5-ethyl-6-[...)
Affinity DataKi:  142nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM365624(6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-1,5-dim...)
Affinity DataKi:  142nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285635(US10077272, Example 1 | 4-[4-(4,6-Dimethylpyrimidi...)
Affinity DataKi:  166nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285654(US10077272, Example 20 | 1-ethyl-6-[4-(furo[2,3-d]...)
Affinity DataKi:  179nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285637(US10077272, Example 3 | 6-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  196nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285652(US10077272, Example 18 | 5-ethyl-6-[4-(furo[2,3-d]...)
Affinity DataKi:  274nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285649(US10077272, Example 15 | 1,5-dimethyl-6-{4-[(3-met...)
Affinity DataKi:  280nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285657(US10077272, Example 23 | 1,5-diethyl-6-[4-(furo[2,...)
Affinity DataKi:  309nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285650(US10077272, Example 16 | 4,6-dimethyl-5-{2-methyl-...)
Affinity DataKi:  326nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285646(US10077272, Example 12 | 5-[4-(1H-imidazo[4,5-c]py...)
Affinity DataKi:  367nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285648(US10077272, Example 14 | 5-[4-(furo[2,3-d]pyrimidi...)
Affinity DataKi:  372nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM365617(4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)...)
Affinity DataKi:  374nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285637(US10077272, Example 3 | 6-[4-(furo[2,3-d]pyrimidin...)
Affinity DataKi:  400nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285653(US10077272, Example 19 | 6-[4-(furo[2,3-d]pyrimidi...)
Affinity DataKi:  900nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285636(US10077272, Example 2 | 4-[3-Methyl-4-(6-methylimi...)
Affinity DataKi:  912nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM285651(US10077272, Example 17 | 1,5-dimethyl-6-{2-methyl-...)
Affinity DataKi:  1.73E+3nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent