Compile Data Set for Download or QSAR
Report error Found 345 Enz. Inhib. hit(s) with all data for entry = 2383
LigandPNGBDBM225901(MAP19 | US9855269, Compound 342)
Affinity DataIC50: 3.11nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 6.20nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299544(US9592235, Example 314 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 7.25nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364098(6-[3-fluoro-5-(4-methyl-1H-pyrazol-3-yl)phenyl]pyr...)
Affinity DataIC50: 10.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299546(US9592235, Example 316 | 3-(4-aminopyrido [3,2-d]p...)
Affinity DataIC50: 11nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299256(US9592235, Example 1 | 6-(2-fluoro-4-pyridyl)pyrid...)
Affinity DataIC50: 11.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011536(CHEMBL3262587 | US9592235, Example 184 | US9855269...)
Affinity DataIC50: 11.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM225896(MAP15 | US9592235, Example 272 | US9855269, Compou...)
Affinity DataIC50: 12.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299492(US9592235, Example 265 | 2-(4-amino- quinazolin- 6...)
Affinity DataIC50: 14.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299462(US9592235, Example 243 | 6-(amino-5-fluoro- phenyl...)
Affinity DataIC50: 16.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299383(US9592235, Example 181 | 6-(3-chloro- phenyl)pyrid...)
Affinity DataIC50: 19.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364053(6-[3-(2-pyridyloxy)phenyl]pyrido[3,2-d]pyrimidin-4...)
Affinity DataIC50: 25.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM363929(US9855269, Compound 172 | 6-[3-(1,4-dimethylpyrazo...)
Affinity DataIC50: 32.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011561(CHEMBL3262580 | US9592235, Example 174 | US9855269...)
Affinity DataIC50: 45.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299537(US9592235, Example 307 | 6-(2-methyl-4- pyridyl)py...)
Affinity DataIC50: 50.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299398(US9592235, Example 191 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 58.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM225898(MAP16 | US9592235, Example 248 | US9855269, Compou...)
Affinity DataIC50: 65.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364073(6-[3-fluoro-5-[(2-pyrrolidin-1-ylethylamino)methyl...)
Affinity DataIC50: 66.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299436(US9592235, Example 225 | N6-[2-(4-fluoro- phenyl)e...)
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299617(US9592235, Example 363 | 6-[3-(difluoro- methoxy)p...)
Affinity DataIC50: 71.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299523(US9592235, Example 297 | 6-[3-(2-pyridyl)-1- piper...)
Affinity DataIC50: 76.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011551(CHEMBL3262570 | US9592235, Example 268 | US9855269...)
Affinity DataIC50: 81.2nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011560(CHEMBL3262579 | US9592235, Example 187 | US9855269...)
Affinity DataIC50: 84nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299592(US9592235, Example 357 | N6-[(3-chloro- phenyl)met...)
Affinity DataIC50: 85.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM225895(MAP14 | US9592235, Example 192 | US9855269, Compou...)
Affinity DataIC50: 88.4nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364028(US9855269, Compound 271 | 6-[3-fluoro-5-(2-pyrroli...)
Affinity DataIC50: 88.8nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299384(US9592235, Example 182 | 6-(5-chloro-2- methyl-phe...)
Affinity DataIC50: 90.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011564(CHEMBL3262583 | MAP10 | US9592235, Example 158 | U...)
Affinity DataIC50: 92.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM363930(US9855269, Compound 173 | 6-[3-(2,4-dimethylpyrazo...)
Affinity DataIC50: 93.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364046(N-[3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-5-fluoro...)
Affinity DataIC50: 95.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364071(N-[[3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-5-fluor...)
Affinity DataIC50: 95.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299619(US9592235, Example 367 | 6-(3-methoxy- phenyl) pyr...)
Affinity DataIC50: 99.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299490(US9592235, Example 263 | N-[3-(4-amino- pyrido[3,2...)
Affinity DataIC50: 107nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364049(6-[3-[(cyclopropylamino)methyl]-5-fluoro-phenyl]py...)
Affinity DataIC50: 110nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364079(6-[3-fluoro-5-[[(1-methylazetidin-3-yl)amino]methy...)
Affinity DataIC50: 124nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364050(2-[[3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-5-fluor...)
Affinity DataIC50: 131nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299488(US9592235, Example 261 | 1-[3-(4-amino- quinazolin...)
Affinity DataIC50: 136nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364037(US9855269, Compound 280 | N-[3-(4-aminopyrido[3,2-...)
Affinity DataIC50: 138nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364056(6-[3-[(cyclobutylamino)methyl]-5-fluoro-phenyl]pyr...)
Affinity DataIC50: 140nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299485(US9592235, Example 258 | 6-[3-(6-methyl-2- pyridyl...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299582(US9592235, Example 352 | 6-(3-chloro- phenoxy) pyr...)
Affinity DataIC50: 145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299412(US9592235, Example 205 | 6-(2-methyl- 4-pyridyl) q...)
Affinity DataIC50: 148nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299494(US9592235, Example 267 | 6-(3-ethoxy- phenyl) quin...)
Affinity DataIC50: 157nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299497(US9592235, Example 270 | N6-benzylpyrido [3,2-d] p...)
Affinity DataIC50: 161nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299397(US9592235, Example 190 | 1-acetyl-N-[3- (4-amino- ...)
Affinity DataIC50: 172nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011559(CHEMBL3262578 | US9592235, Example 269 | US9855269...)
Affinity DataIC50: 174nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM364088(6-[3-[(2-pyrrolidin-1-ylethylamino)methyl]phenyl]p...)
Affinity DataIC50: 177nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM299618(US9592235, Example 365 | 6-(3-isoprapoxy- phenyl) ...)
Affinity DataIC50: 179nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM363961(US9855269, Compound 204 | 1-[[3-(4-aminopyrido[3,2...)
Affinity DataIC50: 186nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

LigandPNGBDBM50011568(CHEMBL3262584 | US9592235, Example 186 | US9855269...)
Affinity DataIC50: 190nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent

Displayed 1 to 50 (of 345 total ) | Next | Last >>
Jump to: