Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 2358
TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362841(US9840508, Compound 3 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataIC50: 20nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362854(US9840508, Compound 16 | (R)-(3-chloro-4- fluoroph...)
Affinity DataIC50: 23nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362853(US9840508, Compound 15 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataIC50: 24nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362851(US9840508, Compound 13 | (R)-(3,4-difluorophenyl)(...)
Affinity DataIC50: 26nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362856(US9840508, Compound 18 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataIC50: 31nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362850(US9840508, Compound 12 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataIC50: 33nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362849(US9840508, Compound 11 | (R)-(3,4-dichlorophenyl)(...)
Affinity DataIC50: 36nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362855(US9840508, Compound 17 | (R)-(4-chloro-3- fluoroph...)
Affinity DataIC50: 37nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362843(US9840508, Compound 5 | (R)-(3,4-difluorophenyl)(8...)
Affinity DataIC50: 52nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362847(US9840508, Compound 9 | (R)-(4-chloro-3- fluorophe...)
Affinity DataIC50: 53nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362845(US9840508, Compound 7 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataIC50: 57nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362852(US9840508, Compound 14 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataIC50: 59nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362839(US9840508, Compound 1 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataIC50: 60nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362846(US9840508, Compound 8 | (R)-(3-chloro-4- fluorophe...)
Affinity DataIC50: 62nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362842(US9840508, Compound 4 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataIC50: 72nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362848(US9840508, Compound 10 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataIC50: 74nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362844(US9840508, Compound 6 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataIC50: 99nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM50081280(CHEMBL3422005 | US9840508, Compound 2)
Affinity DataIC50: 160nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362853(US9840508, Compound 15 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  13nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362853(US9840508, Compound 15 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  13nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362854(US9840508, Compound 16 | (R)-(3-chloro-4- fluoroph...)
Affinity DataKi:  14nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362854(US9840508, Compound 16 | (R)-(3-chloro-4- fluoroph...)
Affinity DataKi:  14nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362851(US9840508, Compound 13 | (R)-(3,4-difluorophenyl)(...)
Affinity DataKi:  20nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362851(US9840508, Compound 13 | (R)-(3,4-difluorophenyl)(...)
Affinity DataKi:  20nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362856(US9840508, Compound 18 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataKi:  21nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362856(US9840508, Compound 18 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataKi:  21nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362855(US9840508, Compound 17 | (R)-(4-chloro-3- fluoroph...)
Affinity DataKi:  22nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362855(US9840508, Compound 17 | (R)-(4-chloro-3- fluoroph...)
Affinity DataKi:  22nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362841(US9840508, Compound 3 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataKi:  22nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362841(US9840508, Compound 3 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataKi:  22nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362849(US9840508, Compound 11 | (R)-(3,4-dichlorophenyl)(...)
Affinity DataKi:  27nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362849(US9840508, Compound 11 | (R)-(3,4-dichlorophenyl)(...)
Affinity DataKi:  27nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362850(US9840508, Compound 12 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  29nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362850(US9840508, Compound 12 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  29nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362845(US9840508, Compound 7 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataKi:  33nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362845(US9840508, Compound 7 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataKi:  33nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362848(US9840508, Compound 10 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataKi:  36nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362848(US9840508, Compound 10 | (R)-(4-chlorophenyl)(8- m...)
Affinity DataKi:  36nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362847(US9840508, Compound 9 | (R)-(4-chloro-3- fluorophe...)
Affinity DataKi:  38nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362847(US9840508, Compound 9 | (R)-(4-chloro-3- fluorophe...)
Affinity DataKi:  38nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362852(US9840508, Compound 14 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  40nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362852(US9840508, Compound 14 | (R)-(8-methyl-3-(2- (trif...)
Affinity DataKi:  40nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362843(US9840508, Compound 5 | (R)-(3,4-difluorophenyl)(8...)
Affinity DataKi:  42nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362843(US9840508, Compound 5 | (R)-(3,4-difluorophenyl)(8...)
Affinity DataKi:  42nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362846(US9840508, Compound 8 | (R)-(3-chloro-4- fluorophe...)
Affinity DataKi:  44nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362846(US9840508, Compound 8 | (R)-(3-chloro-4- fluorophe...)
Affinity DataKi:  44nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362839(US9840508, Compound 1 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataKi:  48nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362839(US9840508, Compound 1 | (R)-(4-fluorophenyl)(8- me...)
Affinity DataKi:  48nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362842(US9840508, Compound 4 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataKi:  52nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Oged

US Patent
LigandPNGBDBM362842(US9840508, Compound 4 | (R)-(8-methyl-3-(5- methyl...)
Affinity DataKi:  52nMAssay Description:The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vitro ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

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