Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2356
TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362838(US9840503, Example 11 | 5-(trans-4-aminocyclohexyl...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362838(US9840503, Example 11 | 5-(trans-4-aminocyclohexyl...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362837(US9840503, Example 10 | 5-(trans-4-Aminocyclohexyl...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362837(US9840503, Example 10 | 5-(trans-4-Aminocyclohexyl...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362836(US9840503, Example 9 | 5-(trans-4-Aminocyclohexyl)...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362836(US9840503, Example 9 | 5-(trans-4-Aminocyclohexyl)...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362836(US9840503, Example 9 | 5-(trans-4-Aminocyclohexyl)...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362831(US9840503, Example 4 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362830(US9840503, Example 3 | trans-4-[3-(Butylamino)-8-[...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362830(US9840503, Example 3 | trans-4-[3-(Butylamino)-8-[...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362830(US9840503, Example 3 | trans-4-[3-(Butylamino)-8-[...)
Affinity DataIC50: 100nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362831(US9840503, Example 4 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362828(US9840503, Example 1 | trans-4-[3-(Butylamino)-8-(...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362828(US9840503, Example 1 | trans-4-[3-(Butylamino)-8-(...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362838(US9840503, Example 11 | 5-(trans-4-aminocyclohexyl...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362837(US9840503, Example 10 | 5-(trans-4-Aminocyclohexyl...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362834(US9840503, Example 7 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362834(US9840503, Example 7 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362829(US9840503, Example 2 | US9840503, Example 6 | 3-(B...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362832(US9840503, Example 5 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362832(US9840503, Example 5 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 550nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362835(US9840503, Example 8 | 3-(Butylamino)-8-(2, 6-difl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase Mer(Human)
Incyte

US Patent
LigandPNGBDBM362835(US9840503, Example 8 | 3-(Butylamino)-8-(2, 6-difl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Incyte

US Patent
LigandPNGBDBM362835(US9840503, Example 8 | 3-(Butylamino)-8-(2, 6-difl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362834(US9840503, Example 7 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362828(US9840503, Example 1 | trans-4-[3-(Butylamino)-8-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362832(US9840503, Example 5 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Incyte

US Patent
LigandPNGBDBM362831(US9840503, Example 4 | 3-(Butylamino)-5-(trans-4-h...)
Affinity DataIC50: 1.00E+3nMAssay Description:The assay buffer contained 50 mM HEPES, pH7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% NP-40 and 2 mM DTT. 0.5 ul test compounds dissolved in DMSO were transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details
Go to US Patent