Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 1852
TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344295BDBM344295((1R*,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- ...)
Affinity DataIC50: 40nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344365BDBM344365((1S,3S*)-3-(1- (Difluoromethyl)-1H- indazol-6-yl)-...)
Affinity DataIC50: 46nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345231BDBM345231((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 48nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344298BDBM344298((1R*,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- ...)
Affinity DataIC50: 50nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345230BDBM345230((1S,3R*)-3-(7-Fluoro-1- methyl-1H-indazol-6-yl)-1-...)
Affinity DataIC50: 55nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345218BDBM345218((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 59nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345232BDBM345232((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 62nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344364BDBM344364((1S,3R*)-3-(1- (Difluoromethyl)-1H- indazol-6-yl)-...)
Affinity DataIC50: 72nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344377BDBM344377((1S,3R*)-3-(7-fluoro-1H-indazol-6-yl)-1-(3-fluoro-...)
Affinity DataIC50: 73nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345221BDBM345221((1S,3R*)-1-(3-Fluoro-2-methylphenyl)-N-hydroxy-3-(...)
Affinity DataIC50: 74nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345222BDBM345222((1S,3S*)-3- (Benzo[d]thiazol-2-yl)-1- (3-fluoro-2-...)
Affinity DataIC50: 80nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344368BDBM344368((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 82nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344359BDBM344359((1S,3R*)-3-(1-(2-(diethylamino)ethyl)-1H-pyrazol-4...)
Affinity DataIC50: 82nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345195BDBM345195((1S,3R*)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-3-(...)
Affinity DataIC50: 90nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345233BDBM345233((1S,3R*)-1-(3,4-difluoro-2-methylphenyl)-N-hydroxy...)
Affinity DataIC50: 90nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344354BDBM344354((1S,3R*)-3-(1-(Difluoromethyl)-1H-pyrazol-4-yl)-1-...)
Affinity DataIC50: 95nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344367BDBM344367((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 98nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345156BDBM345156((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 100nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344297BDBM344297((1S*,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- ...)
Affinity DataIC50: 100nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345160BDBM345160((1S,3R*)-3-(2- (Difluoromethyl)-2H- indazol-6-yl)-...)
Affinity DataIC50: 110nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345229BDBM345229((1S,3S*)-3-(7-Fluoro-1- methyl-1H-indazol-6-yl)-1-...)
Affinity DataIC50: 110nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345153BDBM345153((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 110nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345217BDBM345217((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 110nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345243BDBM345243((1S,3S)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3-...)
Affinity DataIC50: 130nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344301BDBM344301((1S,3R*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluor...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344366BDBM344366((1S,3R*)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-3-(...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344369BDBM344369((1S,3R*)-3-(2-cyclopropyl-1-oxoisoindolin-5-yl)-1-...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345239BDBM345239((1S,3S)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3-...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344355BDBM344355((1S,3R*)-1-(3-fluoro-2-methylphenyl)-N-hydroxy-3-(...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344300BDBM344300((1S,3S*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluor...)
Affinity DataIC50: 150nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344323BDBM344323(1-(3,4-Difluoro-2-methylphenyl)-N- hydroxycyclopen...)
Affinity DataIC50: 150nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345228BDBM345228((1S,3R)-3-(5-Fluoro-1-methyl-1H-indazol-6-yl)-1-(3...)
Affinity DataIC50: 150nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345241BDBM345241((1S,3S)-1-(3-Fluoro-2- methylphenyl)-3-((5- fluoro...)
Affinity DataIC50: 160nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345223BDBM345223((1S,3R*)-3- (Benzo-[d]thiazol-2-yl)-1- (3-fluoro-2...)
Affinity DataIC50: 160nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345242BDBM345242((1S,3R)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3-...)
Affinity DataIC50: 160nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344363BDBM344363(N-((R)-1- (Dipropylamino)propan-2- yl)-4-((1S*,3S)...)
Affinity DataIC50: 160nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344299BDBM344299((+-)-(1S*,3S*)1-(3-fluoro-2-methylphenyl)-N-hydrox...)
Affinity DataIC50: 170nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344357BDBM344357((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 170nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344353BDBM344353((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-3-(5-fluoro-...)
Affinity DataIC50: 190nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344292BDBM344292(1-(3-fluoro-2-methylphenyl)-N-hydroxy-3-(pyridin-3...)
Affinity DataIC50: 190nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345240BDBM345240((1S,3R)-1-(3-Fluoro-2- methylphenyl)-3-((5- fluoro...)
Affinity DataIC50: 200nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344304BDBM344304((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-3-(5- fluoro...)
Affinity DataIC50: 200nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344362BDBM344362(N-((R)-1- (Dipropylamino)propan-2- yl)-4-((1R*,3S)...)
Affinity DataIC50: 200nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345173BDBM345173((1S,3S*)-3-(2- (Difluoromethyl)-2H- indazol-6-yl)-...)
Affinity DataIC50: 220nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344351BDBM344351((1S,3R)-3-(2-cyclopropyl-5-fluoropyridin-3-yl)-1-(...)
Affinity DataIC50: 240nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344305BDBM344305((1S,3R*)-1-(3-Fluoro-2- methylphenyl)-3-(5- fluoro...)
Affinity DataIC50: 240nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345244BDBM345244((1S,3S)-1-(3-fluoro-2-methylphenyl)-3-((4-fluorobe...)
Affinity DataIC50: 240nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344358BDBM344358((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 250nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 345220BDBM345220((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 270nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 344311BDBM344311(1-(3-fluoro-2-methylphenyl)-N-hydroxycyclopentanec...)
Affinity DataIC50: 270nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
US Patent

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