Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 1799
Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340822(US9765040, Compound 14)
Affinity DataIC50: 16nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340823(US9765040, Compound 15)
Affinity DataIC50: 23nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340790(US9765040, Compound 3)
Affinity DataIC50: 24nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340798(US9765040, Compound 9)
Affinity DataIC50: 26nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340791(US9765040, Compound 4)
Affinity DataIC50: 32nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340796(US9765040, Compound 7)
Affinity DataIC50: 32nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340548(US9765040, Compound 1)
Affinity DataIC50: 35nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340642(US9765040, Compound 2)
Affinity DataIC50: 52nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340803(US9765040, Compound 11)
Affinity DataIC50: 64nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340814(US9765040, Compound 13)
Affinity DataIC50: 68nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340797(US9765040, Compound 8)
Affinity DataIC50: 70nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340799(US9765040, Compound 10)
Affinity DataIC50: 135nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
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Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340810(US9765040, Compound 12)
Affinity DataIC50: 182nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340792(US9765040, Compound 5)
Affinity DataIC50: 263nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM340793(US9765040, Compound 6)
Affinity DataIC50: 322nMAssay Description:The procedure for measuring the 11β-HSD1-inhibitory activity is as follows. The enzyme reaction and the measurement were carried out using a 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent