Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 1687
TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335698(US9738626, 1 (free base) | (R)-3-(3-Methyl-2-oxopi...)
Affinity DataKi:  3.30nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335700(US9738626, 3 (TFA salt) | (R)-6-(5-Ethylquinolin-7...)
Affinity DataKi:  4.60nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335699(US9738626, 2 (free base and TFA salt) | (R)-3-(3-M...)
Affinity DataKi:  7.20nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335702(US9738626, 5 (TFA salt) | (R)-6-(5-Cyclopropylquin...)
Affinity DataKi:  7.30nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335701(US9738626, 4 (free base and TFA salt) | (R)-6-(5-C...)
Affinity DataKi:  8.90nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335704(US9738626, 7 (formate salt) | (R)-3-(3-Methyl-2-ox...)
Affinity DataKi:  18.6nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335703(US9738626, 6 (TFA salt) | (R)-3-(6-(5-fluoroquinol...)
Affinity DataKi:  48.6nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent