Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 1556
TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50209206((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Affinity DataIC50: 3.40E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 8.30E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158465((4-hydroxy-3,5-diiodophenyl)(2-methylbenzofuran-3-...)
Affinity DataIC50: 8.30E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM18964(NSC85438 | 4-[(2-butyl-1-benzofuran-3-yl)carbonyl]...)
Affinity DataIC50: 1.01E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.10E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM330348(US9725430, Compound 1e | US9962362, Compound 1e)
Affinity DataIC50: 1.38E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM18964(NSC85438 | 4-[(2-butyl-1-benzofuran-3-yl)carbonyl]...)
Affinity DataIC50: 1.52E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342278((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Affinity DataIC50: 1.70E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM330350(US9725430, Compound 1f | US9962362, Compound 1f)
Affinity DataIC50: 1.75E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3 [223-510](Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342278((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Affinity DataIC50: 1.92E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342279((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...)
Affinity DataIC50: 2.72E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342287((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Affinity DataIC50: 4.08E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM330353(US9725430, Compound 1i | US9962362, Compound 1i)
Affinity DataIC50: 4.19E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 5.38E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM18964(NSC85438 | 4-[(2-butyl-1-benzofuran-3-yl)carbonyl]...)
Affinity DataIC50: 7.14E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342276((2-Ethyl-5-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...)
Affinity DataIC50: 7.31E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetEyes absent homolog 3(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158457((4-hydroxyphenyl)(2-methylbenzofuran-3-yl)methanon...)
Affinity DataIC50: 8.11E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342278((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Affinity DataIC50: 1.50E+5nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent