Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 273
TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261650(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 33.1nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261649(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 44.6nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261652(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 46.7nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261651(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 55.6nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261671(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triis...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261636(N-(4-(3,4-bis((2-(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261647(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 360nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261652(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 385nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261649(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261650(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 428nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261639(N-(4-(3,4-bis((triisopropylsilyl)ethynyl)phenyl)th...)
Affinity DataIC50: 540nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261639(N-(4-(3,4-bis((triisopropylsilyl)ethynyl)phenyl)th...)
Affinity DataIC50: 540nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261638(N-(4-(3-methyl-4-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261638(N-(4-(3-methyl-4-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50: 640nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261644(N-(4-(3-(3-((tert-butyldiphenylsilyl)oxy)prop-1-yn...)
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261637(N-(4-(4-methyl-3-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50: 710nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261653(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(3-(tri...)
Affinity DataIC50: 830nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261648(N-(4-(3-((tert-butyldiphenylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 870nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261671(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triis...)
Affinity DataIC50: 910nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261659(N-(4-(4-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261645(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(3-((tr...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261666(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261637(N-(4-(4-methyl-3-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261647(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261644(N-(4-(3-(3-((tert-butyldiphenylsilyl)oxy)prop-1-yn...)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261640(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((triet...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261648(N-(4-(3-((tert-butyldiphenylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261635(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((2-(tr...)
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261659(N-(4-(4-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261630(N-(4-(4-methyl-3-((2-(trifluoromethyl)phenyl)ethyn...)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261658(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(4-((triis...)
Affinity DataIC50: 1.90E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261660(N-(4-(4-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261653(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(3-(tri...)
Affinity DataIC50: 2.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261651(5-(4-(4-methylpiperazine-1-carbonyl)phenyl)-N-(4-(...)
Affinity DataIC50: 2.13E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261661(4-(morpholinomethyl)-N-(4-(3-((triisopropylsilyl)e...)
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261634(N-(4-(3-methyl-4-((2-(trifluoromethyl)phenyl)ethyn...)
Affinity DataIC50: 2.40E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261633(N-(4-(3-methyl-4-(p-tolylethynyl)phenyl)thiazol-2-...)
Affinity DataIC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261628(N-(4-(4-methyl-3-(p-tolylethynyl)phenyl)thiazol-2-...)
Affinity DataIC50: 2.70E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261664(N-(4-(3-((tert-butyldiphenylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 2.70E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261673(4-((4-(prop-2-yn-1-yl)piperazin-1-yl)methyl)-N-(4-...)
Affinity DataIC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261656(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261636(N-(4-(3,4-bis((2-(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261673(4-((4-(prop-2-yn-1-yl)piperazin-1-yl)methyl)-N-(4-...)
Affinity DataIC50: 3.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261665(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-((2-(tr...)
Affinity DataIC50: 3.70E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261656(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: 4.10E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261645(4-((4-methylpiperazin-1-yl)methyl)-N-(4-(3-(3-((tr...)
Affinity DataIC50: 4.20E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261663(N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 4.40E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261660(N-(4-(4-((tert-butyldimethylsilyl)ethynyl)phenyl)t...)
Affinity DataIC50: 4.60E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor [L1196M](Human)
UniversitÁ

US Patent
LigandPNGBDBM261626(N-(4-(3-((4-methoxyphenyl)ethynyl)phenyl)thiazol-2...)
Affinity DataIC50: 4.80E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetALK tyrosine kinase receptor(Human)
UniversitÁ

US Patent
LigandPNGBDBM261654(N-(4-(3-((2-fluorophenyl)ethynyl)phenyl)thiazol-2-...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

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