Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 251
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254012(racemic 4-[(2'R,3R,3'S,5'S)-6-chloro-3'-(3-chloro-...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254013(US9701685, 20 | racemic (4-carbamoyl-2-methoxy-phe...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254014(chiral 4-[(2'R,3R,3'S,5'S)-6-chloro-3'-(3-chloro-2...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254013(US9701685, 20 | racemic (4-carbamoyl-2-methoxy-phe...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254009(US9701685, 11 | US9701685, 27 | racemic 4-[[(2''R,...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254011(US9701685, 13 | racemic (2''R,3R,3''S,5''S)-N-(4-c...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254008(US9701685, 10 | racemic 4-[[(2''R,3R,3''S,5''S)-6-...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254010(US9701685, 12 | US9701685, 66 | racemic (2''R,3R,3...)
Affinity DataIC50: 3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254025(chiral (2'R,3R,3'S,5'S)-N-(4-carbamoyl-2-methoxy-p...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254008(US9701685, 10 | racemic 4-[[(2''R,3R,3''S,5''S)-6-...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254024(chiral 4-[[(2'R,3R,3'S,5'S)-6-chloro-3'-(3-chloro-...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254023(racemic 6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254022(racemic 4-{[6-chloro-4'-(3-chloro-2-fluoro-phenyl)...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254021(racemic 4-{[6-chloro-4'-(3-chloro-2-fluoro-phenyl)...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254016(chiral ethyl-4-[[(2'R,3'R,3'S,5'S)-6-chloro-3'(3-c...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254011(US9701685, 13 | racemic (2''R,3R,3''S,5''S)-N-(4-c...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254010(US9701685, 12 | US9701685, 66 | racemic (2''R,3R,3...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Hudson Biopharma

US Patent
LigandPNGBDBM254009(US9701685, 11 | US9701685, 27 | racemic 4-[[(2''R,...)
Affinity DataIC50: 7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent