Compile Data Set for Download or QSAR
Report error Found 363 Enz. Inhib. hit(s) with all data for entry = 11368
TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610355(N-(5-amino-2-((dimethylamino)methyl)phenyl)-2-meth...)
Affinity DataIC50: 1nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610135((R)-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbox...)
Affinity DataIC50: 2nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610136(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 3nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610145(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 3nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610132(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610133(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610137(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 4nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610253(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 4nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234073(CHEMBL4063330 | US9701664, Example 1)
Affinity DataIC50: 5nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610355(N-(5-amino-2-((dimethylamino)methyl)phenyl)-2-meth...)
Affinity DataIC50: 5nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataIC50: 6nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234090(CHEMBL4069552 | US9701664, Example 2)
Affinity DataIC50: 7nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610022(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 7nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610140((S)-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbox...)
Affinity DataIC50: 7nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610140((S)-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbox...)
Affinity DataIC50: 7nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610143(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 7nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50: 7nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610162((S)-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbox...)
Affinity DataIC50: 7nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234074(CHEMBL4070633 | US9701664, Example 39)
Affinity DataIC50: 8nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610135((R)-N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carbox...)
Affinity DataIC50: 8nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610023(N-(4-methyl-3-(2-oxo-2H-chromene-6-carboxamido)phe...)
Affinity DataIC50: 10nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610136(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 10nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610137(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 10nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610143(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 10nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610181(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 10nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610256(N-(2-bromo-5-(2,3-dihydrobenzo[b][1,4]dioxine-6-ca...)
Affinity DataIC50: 10nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610377(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 10nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610128(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 11nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610132(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 12nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610133(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 12nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataIC50: 12nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610167(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 12nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610144(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 13nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610145(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 13nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610149(2-(2-(azetidin-1-yl)ethoxy)-N-(5-(2,3-dihydrobenzo...)
Affinity DataIC50: 13nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234085(CHEMBL4102297 | US9701664, Example 89)
Affinity DataIC50: 13nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610376(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 13nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234073(CHEMBL4063330 | US9701664, Example 1)
Affinity DataIC50: 14nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610253(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 14nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610358(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 14nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610030(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 15nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610147(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 15nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610148(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 15nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50234085(CHEMBL4102297 | US9701664, Example 89)
Affinity DataIC50: 15nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610255(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 15nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610149(2-(2-(azetidin-1-yl)ethoxy)-N-(5-(2,3-dihydrobenzo...)
Affinity DataIC50: 16nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610150(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 16nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610158(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 16nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610025(N-(3-(2,3-dihydrobenzofuran-5-carboxamido)-4-methy...)
Affinity DataIC50: 17nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent

TargetHeat shock factor protein 1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM610158(N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamid...)
Affinity DataIC50: 17nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
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