Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 33
TargetEnvelope glycoprotein gp160(HIV-1)
Chimerix

US Patent
LigandPNGBDBM77108(CMX157-220)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
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Date in BDB:
1/19/2018
Entry Details
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TargetEnvelope glycoprotein gp160(HIV-1)
Chimerix

US Patent
LigandPNGBDBM77105(CMX157-211)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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TargetEnvelope glycoprotein gp160(HIV-1)
Chimerix

US Patent
LigandPNGBDBM77097(CMX157-210)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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TargetEnvelope glycoprotein gp160(HIV-1)
Chimerix

US Patent
LigandPNGBDBM77141(CMX157 ion)
Affinity DataEC50: <30nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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TargetEnvelope glycoprotein gp160(HIV-1)
Chimerix

US Patent
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:The in vitro antiviral activity profile for CMX157 was evaluated for cell-type effects and HIV strain effects. It is active against all major subtype...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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TargetGag-Pol polyprotein [588-1147,K652R,M771V](HIV-1)
Chimerix

US Patent
LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 1.80nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
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Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 3.10nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 3.80nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 5nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 9nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
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Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77092(CMX-157 | HDP-tenofovir | hexadecyloxypropyl 9-(2-...)
Affinity DataIC50: 19nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
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Date in BDB:
1/19/2018
Entry Details
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TargetGag-Pol polyprotein [588-1147,K652R,M771V](HIV-1)
Chimerix

US Patent
LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 1.04E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 5.39E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 6.47E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 6.49E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 6.52E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
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LigandPNGBDBM77145(9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)ph...)
Affinity DataIC50: 8.51E+3nMAssay Description:The PhenoSense report form includes drug resistance information for all of the approved nucleoside reverse transcriptase inhibitors (NRTIs), nonnucle...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
Go to US Patent