Compile Data Set for Download or QSAR
Report error Found 114 Enz. Inhib. hit(s) with all data for entry = 126
LigandPNGBDBM164395(US9669029, 98 8-Methoxy-5-methyl-2-{2-[1-(2-morpho...)
Affinity DataIC50: 0.330nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164399(US9669029, 102 5,8-Dimethyl-2-[2-(1-methyl-4-thiop...)
Affinity DataIC50: 0.390nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164544(US9669029, 115 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164545(US9669029, 116 5,8-Dimethyl-2-[2-(1-methyl-4-pyrim...)
Affinity DataIC50: 0.440nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164549(US9669029, 117 5,8-Dimethyl-2-[2-(1-methyl-4-pyraz...)
Affinity DataIC50: 0.520nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164283(US9669029, 33 5-Methyl-2-[2-(4-thiophen-2-yl-1H-im...)
Affinity DataIC50: 0.540nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164560(US9669029, 118 5,8-Dimethyl-2-[2-(1-methyl-4-pyrid...)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164284(US9669029, 34 8-Methyl-2-[2-(4-thiophen-2-yl-1H-im...)
Affinity DataIC50: 0.990nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164391(US9669029, 94 5,8-Dimethyl-2-[2-(1-methyl-4-thioph...)
Affinity DataIC50: 1nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164354(US9669029, 93 8-Methoxy-5-methyl-2-[2-(4-thiophen-...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164392(US9669029, 95 8-Methoxy-5-methyl-2-[2-(1-propyl-4-...)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164543(US9669029, 114 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 1.29nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164354(US9669029, 93 8-Methoxy-5-methyl-2-[2-(4-thiophen-...)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164394(US9669029, 97 4-{2-[2-(8-Methoxy-5-methyl-[1,2,4]t...)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164396(US9669029, 99 8-Methoxy-5-methyl-2-[2-(1-methyl-4-...)
Affinity DataIC50: 1.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164495(US9669029, 103 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 2.30nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164316(US9669029, 50 8-Methoxy-5-methyl-2-[(E)-2-(1-methy...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164501(US9669029, 104 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 2.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164350(US9669029, 59 (R)-1-Chloro-3-{2-[2-(5-methyl-[1,2,...)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164536(US9669029, 111 2-[2-(4-Furan-3-yl-1-methyl-1H-imid...)
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164511(US9669029, 105 8-Methoxy-5-methyl-2-{2-[1-methyl-4...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173102(US9669029, 23 5,7-Dimethyl-2-[2-(1-propyl-4-thioph...)
Affinity DataIC50: 3.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164397(US9669029, 100 2-[2-(4-Furan-3-yl-1-methyl-1H-imid...)
Affinity DataIC50: 4nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164393(US9669029, 96 8-Methoxy-5-methyl-2-[2-(1-prop-2-yn...)
Affinity DataIC50: 4.10nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164317(US9669029, 51 5,7-Dimethyl-2-[2-(1-methyl-4-thioph...)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164534(US9669029, 109 5,8-Dimethyl-2-{2-[1-methyl-4-(5-me...)
Affinity DataIC50: 4.20nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164328(US9669029, 55 8-Methoxy-2-[2-(1-methyl-4-thiazol-5...)
Affinity DataIC50: 4.5nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164282(US9669029, 32 1-(4-Chloro-phenyl)-2-{2-[2-(5,7-dim...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164290(US9669029, 40 5-Methyl-2-[2-(4-thiophen-3-yl-1H-im...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164532(US9669029, 107 5,8-Dimethyl-2-[2-(1-methyl-4-pyrid...)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164285(US9669029, 35 (S)-2-{2-[2-(5-Methyl-[1,2,4]triazol...)
Affinity DataIC50: 6.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173105(US9669029, 26 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164398(US9669029, 101 5,8-Dimethyl-2-{2-[1-methyl-4-(5-me...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164539(US9669029, 113 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 6.90nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164286(US9669029, 36 1-Methoxy-3-{2-[2-(5-methyl-[1,2,4]t...)
Affinity DataIC50: 7.5nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173096(US9669029, 17 5,7-Dimethyl-2-[2-(4-thiophen-2-yl-1...)
Affinity DataIC50: 7.60nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164272(US9669029, 22 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]...)
Affinity DataIC50: 7.90nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164380(US9669029, 83 1-Methoxy-3-{2-[2-(8-methyl-[1,2,4]t...)
Affinity DataIC50: 8.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173083(US9669029, 3 5,7-Dimethyl-2-[(E)-2-(1-methyl-4-thi...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173100(US9669029, 21 (S)-2-{2-[2-(5,7-Dimethyl-imidazo[1,...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164372(US9669029, 75 [((S)-2-Hydroxy-3-{2-[2-(5-methyl-[1...)
Affinity DataIC50: 8.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164533(US9669029, 108 5,8-Dimethyl-2-[2-(1-methyl-4-pyrid...)
Affinity DataIC50: 8.90nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164381(US9669029, 84 5-Methyl-2-[2-(1-methyl-4-thiophen-2...)
Affinity DataIC50: 9.20nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164388(US9669029, 91 8-Methoxy-5-methyl-2-[2-(1-methyl-4-...)
Affinity DataIC50: 9.20nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164266(US9669029, 16 5,7-Dimethyl-2-{2-[4-thiophen-2-yl-1...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164291(US9669029, 42 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imi...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164291(US9669029, 42 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imi...)
Affinity DataIC50: 9.60nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164277(US9669029, 27 2-[2-(1-Isobutyl-4-thiophen-2-yl-1H-...)
Affinity DataIC50: 12nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM164531(US9669029, 106 5,8-Dimethyl-2-[2-(1-methyl-4-thiaz...)
Affinity DataIC50: 12nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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LigandPNGBDBM173108(US9669029, 29 1-{2-[2-(5,7-Dimethyl-imidazo[1,2-a]...)
Affinity DataIC50: 14nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
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