Compile Data Set for Download or QSAR
Report error Found 136 Enz. Inhib. hit(s) with all data for entry = 1535
TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330195(US9663530, Example 39 | 3-Chloro-N-[4-[[(1R,4R)-5-...)
Affinity DataIC50: 2.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330161(US9663530, Example 5 | (RS)-4-Chloro-N-[4-(5-oxa-2...)
Affinity DataIC50: 2.80nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330177(US9663530, Example 21 | 4-Chloro-N-[4-[[(1R,4R)-5-...)
Affinity DataIC50: 3nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330211(US9663530, Example 55 | 3-Chloro-N-[4-[(1R,4S)-5-o...)
Affinity DataIC50: 3.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330162(US9663530, Example 6 | 3-Chloro-N-[4-(5-oxa-2-azab...)
Affinity DataIC50: 4.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330200(US9663530, Example 44 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 4.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330222(US9663530, Example 66 | (RS)-1-(4-Chlorophenyl)-3-...)
Affinity DataIC50: 5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330210(US9663530, Example 54 | 4-Chloro-N-[4-[(1R,4S)-5-o...)
Affinity DataIC50: 5.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330215(US9663530, Example 59 | 3-Chloro-N-[4-[(1S,4R)-5-o...)
Affinity DataIC50: 5.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330201(US9663530, Example 45 | 4-(Cyclopropylmethoxy)-N-[...)
Affinity DataIC50: 6.10nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330176(US9663530, Example 20 | 5-Chloro-N-[4-[(1R,4S)-5-o...)
Affinity DataIC50: 6.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330205(US9663530, Example 49 | 4-Ethoxy-N-[4-[[(1R,4R)-5-...)
Affinity DataIC50: 6.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330180(US9663530, Example 24 | 1-(3-Chlorophenyl)-3-[4-[[...)
Affinity DataIC50: 8.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330203(US9663530, Example 47 | N-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 10.4nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330203(US9663530, Example 47 | N-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 10.4nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330219(US9663530, Example 63 | N-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 10.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330200(US9663530, Example 44 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 10.8nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330160(US9663530, Example 4 | (RS)—N-[4-(5-Oxa-2-aza...)
Affinity DataIC50: 11.1nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330224(US9663530, Example 68 | (RS)-1-(3-Chlorophenyl)-3-...)
Affinity DataIC50: 11.9nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330199(US9663530, Example 43 | 1-(2-Chlorophenyl)-3-[4-[[...)
Affinity DataIC50: 12.4nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330178(US9663530, Example 22 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 12.6nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330183(US9663530, Example 27 | N-[4-[[(1 S,4S)-5-Oxa-2-az...)
Affinity DataIC50: 13nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330190(US9663530, Example 34 | (RS)-4-Chloro-N-[4-(5-oxa-...)
Affinity DataIC50: 13.5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330179(US9663530, Example 23 | 1-(4-Chlorophenyl)-3-[4-[[...)
Affinity DataIC50: 13.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330223(US9663530, Example 67 | (RS)-1-[4-(5-Oxa-2-azabicy...)
Affinity DataIC50: 13.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330159(US9663530, Example 3 | (RS)-5-Chloro-N-[4-(5-oxa-2...)
Affinity DataIC50: 14.1nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330202(US9663530, Example 46 | 6-Ethoxy-N-[4-[[(1R,4R)-5-...)
Affinity DataIC50: 14.2nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330217(US9663530, Example 61 | N-[4-[(1 S,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 14.6nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330204(US9663530, Example 48 | 4-Chloro-3-cyclopropyl-N-[...)
Affinity DataIC50: 14.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330209(US9663530, Example 53 | 4-Ethoxy-N-[4-(5-oxa-2-aza...)
Affinity DataIC50: 15.6nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330198(US9663530, Example 42 | US9663530, Example 64 | 5-...)
Affinity DataIC50: 15.8nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330214(US9663530, Example 58 | 4-Chloro-N-[4-[(1S,4R)-5-o...)
Affinity DataIC50: 16nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330181(US9663530, Example 25 | 4-(Cyclopropylmethoxy)-N-[...)
Affinity DataIC50: 17.5nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330197(US9663530, Example 41 | 4-Chloro-N-[4-[[(1R,4R)-5-...)
Affinity DataIC50: 18.3nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330167(US9663530, Example 11 | (RS)-4-(Cyclopropylmethoxy...)
Affinity DataIC50: 19nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330166(US9663530, Example 10 | 1-[4-[[(1S,4S)-5-Oxa-2-aza...)
Affinity DataIC50: 20.9nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330201(US9663530, Example 45 | 4-(Cyclopropylmethoxy)-N-[...)
Affinity DataIC50: 21.2nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330168(US9663530, Example 12 | (RS)-6-Ethoxy-N-[4-(5-oxa-...)
Affinity DataIC50: 21.9nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330178(US9663530, Example 22 | 1-[4-[[(1R,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 23.7nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330223(US9663530, Example 67 | (RS)-1-[4-(5-Oxa-2-azabicy...)
Affinity DataIC50: 26.3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330217(US9663530, Example 61 | N-[4-[(1 S,4R)-5-Oxa-2-aza...)
Affinity DataIC50: 29.3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330198(US9663530, Example 42 | US9663530, Example 64 | 5-...)
Affinity DataIC50: 30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330169(US9663530, Example 13 | (RS)—N-[4-(5-Oxa-2-az...)
Affinity DataIC50: 30.4nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330179(US9663530, Example 23 | 1-(4-Chlorophenyl)-3-[4-[[...)
Affinity DataIC50: 37.5nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330193(US9663530, Example 37 | (RS)—N-[4-(5-Oxa-2-az...)
Affinity DataIC50: 37.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330212(US9663530, Example 56 | N-[4-[(1R,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 39.3nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330163(US9663530, Example 7 | 5-Chloro-N-[4-[(1S,4R)-5-ox...)
Affinity DataIC50: 41.4nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330164(US9663530, Example 8 | 1-[4-[[(1S,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 44.2nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330222(US9663530, Example 66 | (RS)-1-(4-Chlorophenyl)-3-...)
Affinity DataIC50: 46.5nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330192(US9663530, Example 36 | N-[4-(5-Oxa-2-azabicyclo[2...)
Affinity DataIC50: 47.1nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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