Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 1436
TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 0.0100nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)
Affinity DataIC50: 2.60nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153445(CHEMBL3775280 | US9630914, Example 15)
Affinity DataIC50: 3.30nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)
Affinity DataIC50: 4nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)
Affinity DataIC50: 6nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 8.60nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153366(CHEMBL3774467 | US9630914, Example 5)
Affinity DataIC50: 9nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153445(CHEMBL3775280 | US9630914, Example 15)
Affinity DataIC50: 9.10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 9.40nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 9.70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 9.90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 10nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 10nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)
Affinity DataIC50: 11nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 12nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153373(CHEMBL3774805 | US9630914, Example 9)
Affinity DataIC50: 13nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153446(CHEMBL3775770 | US9630914, Example 16)
Affinity DataIC50: 16nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153366(CHEMBL3774467 | US9630914, Example 5)
Affinity DataIC50: 18nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)
Affinity DataIC50: 20nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153372(CHEMBL3774586 | US9630914, Example 8)
Affinity DataIC50: 22nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153373(CHEMBL3774805 | US9630914, Example 9)
Affinity DataIC50: 27nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153442(CHEMBL3774442 | US9630914, Example 18)
Affinity DataIC50: 30nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 31nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 31nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153446(CHEMBL3775770 | US9630914, Example 16)
Affinity DataIC50: 63nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153371(CHEMBL3775973 | US9630914, Example 7)
Affinity DataIC50: 70nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153372(CHEMBL3774586 | US9630914, Example 8)
Affinity DataIC50: 90nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)
Affinity DataIC50: 92nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 150nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153366(CHEMBL3774467 | US9630914, Example 5)
Affinity DataIC50: 150nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)
Affinity DataIC50: 160nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153442(CHEMBL3774442 | US9630914, Example 18)
Affinity DataIC50: 170nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153371(CHEMBL3775973 | US9630914, Example 7)
Affinity DataIC50: 170nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153446(CHEMBL3775770 | US9630914, Example 16)
Affinity DataIC50: 240nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153376(CHEMBL3774439 | US9630914, Example 10)
Affinity DataIC50: 260nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153365(CHEMBL3774541 | US9630914, Example 4)
Affinity DataIC50: 280nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)
Affinity DataIC50: 320nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153365(CHEMBL3774541 | US9630914, Example 4)
Affinity DataIC50: 360nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153379(CHEMBL3775979 | US9630914, Example 13)
Affinity DataIC50: 370nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 430nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153378(CHEMBL3775041 | US9630914, Compound 12)
Affinity DataIC50: 430nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153377(CHEMBL3775104 | US9630914, Example 11)
Affinity DataIC50: 570nMAssay Description:Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153372(CHEMBL3774586 | US9630914, Example 8)
Affinity DataIC50: 580nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153365(CHEMBL3774541 | US9630914, Example 4)
Affinity DataIC50: 600nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153439(CHEMBL3775610 | US9630914, Example 17)
Affinity DataIC50: 720nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153439(CHEMBL3775610 | US9630914, Example 17)
Affinity DataIC50: 740nMAssay Description:Human recombinant FAAH was obtained from a HEK-293 FAAH-1 overexpressing stable cell line. Cells were grown in DMEM medium containing 10% FBS, 1% pen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153438(CHEMBL3774873 | US9630914, Example 14)
Affinity DataIC50: 990nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50074922(2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...)
Affinity DataIC50: 1.04E+3nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

US Patent
LigandPNGBDBM50153445(CHEMBL3775280 | US9630914, Example 15)
Affinity DataIC50: 1.10E+3nMAssay Description:COX activity was measured using a commercial kit (COX Inhibitor Screening Assay Kit Cayman Chemical N. 560131) which includes both ovine COX-1 and hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2019
Entry Details
Go to US Patent

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