Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 1327
LigandChemical structure of BindingDB Monomer ID 317168BDBM317168(US9617271, 26 | (E)-8-Isopropoxy-2,3-dimethyl-6-(2...)
Affinity DataIC50: 0.493nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317193BDBM317193(US9617271, 51 | 7-Cyclobutyl-2,3-dimethyl-6-((1-me...)
Affinity DataIC50: 0.600nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317189BDBM317189(US9617271, 47 | 8-Cyclobutyl-2,3-dimethyl-6-((1-me...)
Affinity DataIC50: 0.900nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317151BDBM317151((E)-8-methoxy-3-methyl-6-(2-(1-methyl-3-(pyrrolidi...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317167BDBM317167(US9617271, 25 | 8-Isopropoxy-2,3-dimethyl-6-((1-me...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317182BDBM317182(US9617271, 40 | N,2,3-Trimethyl-6-((1-methyl-3-(py...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317186BDBM317186(US9617271, 44 | 8-Isopropyl-2,3-dimethyl-6-((1-met...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317188BDBM317188(US9617271, 46 | 8-Cyclopropyl-2,3-dimethyl-6-((1-m...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317159BDBM317159(US9617271, 17 | 2,3,7-Trimethyl-6-((1-methyl-3-(py...)
Affinity DataIC50: 1nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317180BDBM317180(US9617271, 38 | 2-Chloro-3-methyl-6-((1-methyl-3-(...)
Affinity DataIC50: 1.33nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317177BDBM317177(US9617271, 35 | N,N-Diethyl-6,7-dimethyl-2-(2-(1-m...)
Affinity DataIC50: 1.41nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317196BDBM317196(US9617271, 54 | 3,8-Dimethyl-6-((1-methyl-3-(pyrro...)
Affinity DataIC50: 1.60nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317164BDBM317164(US9617271, 22 | N,N,6,7-Tetramethyl-2-(2-(1-methyl...)
Affinity DataIC50: 2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317183BDBM317183(US9617271, 41 | N,2,3-Trimethyl-6-(2-(1-methyl-3-(...)
Affinity DataIC50: 2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317152BDBM317152(8-Methoxy-3-methyl-6-(2-(1-methyl-3-(pyrrolidin-1-...)
Affinity DataIC50: 2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317155BDBM317155(US9617271, 13 | 4-Methoxy-6,7-dimethyl-2-(2-(1-met...)
Affinity DataIC50: 2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317158BDBM317158(US9617271, 16 | 2,3,8-trimethyl-6-(2-(1-methyl-3-(...)
Affinity DataIC50: 2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317211BDBM317211(US9617271, 69 | N,3-Dimethyl-6-((1-methyl-3-(pyrro...)
Affinity DataIC50: 2.10nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317195BDBM317195(US9617271, 53 | 2,3-dimethyl-5-(2-(1-methyl-3-(pyr...)
Affinity DataIC50: 2.10nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317190BDBM317190(US9617271, 48 | 8-Cyclobutyl-2,3-dimethyl-6-(2-(1-...)
Affinity DataIC50: 2.30nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317207BDBM317207(US9617271, 65 | 3-Chloro-2-methyl-6-((1-methyl-3-(...)
Affinity DataIC50: 2.5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317194BDBM317194(US9617271, 52 | 2,3-Dimethyl-5-((1-methyl-3-(pyrro...)
Affinity DataIC50: 2.60nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317192BDBM317192(US9617271, 50 | 7-Isopropyl-2,3-dimethyl-6-((1-met...)
Affinity DataIC50: 2.60nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317202BDBM317202(US9617271, 60 | 7-Methoxy-2,3-dimethyl-6-((1-methy...)
Affinity DataIC50: 2.70nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317191BDBM317191(US9617271, 49 | 8-Cyclopropyl-2,3-dimethyl-6-(2-(1...)
Affinity DataIC50: 2.90nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317169BDBM317169(US9617271, 27 | 8-Isopropoxy-2,3-dimethyl-6-(2-(1-...)
Affinity DataIC50: 3nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317154BDBM317154(US9617271, 12 | 8-Methoxy-2,3-dimethyl-6-(2-(1-met...)
Affinity DataIC50: 3nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317173BDBM317173(US9617271, 31 | N-Isopropyl-6,7-dimethyl-2-(2-(1-m...)
Affinity DataIC50: 3nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317204BDBM317204(US9617271, 62 | 3-Methyl-6-((1-methyl-3-(pyrrolidi...)
Affinity DataIC50: 3nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317146BDBM317146(3-Methyl-6-((1-methyl-5-(pyrrolidin-1-yl)-1H-1,2,4...)
Affinity DataIC50: 4nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317157BDBM317157(US9617271, 15 | 4-Chloro-6,7-dimethyl-2-(2-(1-meth...)
Affinity DataIC50: 4nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317149BDBM317149(2-(Difluoromethyl)-3-methyl-6-((1-methyl-3-(pyrrol...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317171BDBM317171(US9617271, 29 | 2,3-Dimethyl-6-((1-methyl-3-(pyrro...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317145BDBM317145(3-Methyl-6-[(E)-2-(2-methyl-5-pyrrolidin-1-yl-2H-[...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317161BDBM317161(US9617271, 19 | 2,3-Dimethyl-6-(2-(1-methyl-3-(pyr...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317176BDBM317176(US9617271, 34 | N-Ethyl-N,6,7-trimethyl-2-(2-(1-me...)
Affinity DataIC50: 5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317206BDBM317206(US9617271, 64 | 2-Chloro-3-methyl-6-(2-(1-methyl-3...)
Affinity DataIC50: 5.5nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317166BDBM317166(US9617271, 24 | 2,3-Dimethyl-6-(2-(1-methyl-3-(pyr...)
Affinity DataIC50: 6nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317174BDBM317174(US9617271, 32 | N-Ethyl-6,7-dimethyl-2-(2-(1-methy...)
Affinity DataIC50: 6nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317201BDBM317201(US9617271, 59 | 2,3,6-Trimethyl-5-((1-methyl-3-(py...)
Affinity DataIC50: 6.60nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317150BDBM317150(2-(Difluoromethyl)-3-methyl-6-(2-(1-methyl-3-(pyrr...)
Affinity DataIC50: 8nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317213BDBM317213(US9617271, 71 | 3-Methyl-5-[2-(2-methyl-5-pyrrolid...)
Affinity DataIC50: 8.70nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317187BDBM317187(US9617271, 45 | 8-Isopropyl-2,3-dimethyl-6-(2-(1-m...)
Affinity DataIC50: 9nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317205BDBM317205(US9617271, 63 | 3-Methyl-6-(2-(1-methyl-3-(pyrroli...)
Affinity DataIC50: 9.40nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317209BDBM317209(US9617271, 67 | 2-Methyl-6-((1-methyl-3-(pyrrolidi...)
Affinity DataIC50: 10.2nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317162BDBM317162(US9617271, 20 | 4-Chloro-6,7-dimethyl-2-(2-(1-meth...)
Affinity DataIC50: 11nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317184BDBM317184(US9617271, 42 | 2,3-Dimethyl-6-((1-methyl-3-(pyrro...)
Affinity DataIC50: 11nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317142BDBM317142(2,3-Dimethyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H...)
Affinity DataIC50: 11nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 317138BDBM317138(3-Methyl-6-(2-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2...)
Affinity DataIC50: 12nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 317212BDBM317212(US9617271, 70 | N,3-dimethyl-6-(2-(1-methyl-3-(pyr...)
Affinity DataIC50: 13.7nMAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

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