Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 1272
TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM50134187(CHEMBL3735506 | US9611249, Compound 8 | US11472795...)
Affinity DataIC50: 20nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314399(US9611249, Compound 30 | {4-[({[5-(5-methoxypyridi...)
Affinity DataIC50: 20nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314371(US9611249, Compound 4 | N-{[1-(2-methoxyethyl)pipe...)
Affinity DataIC50: 30nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314382(US9611249, Compound 10 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 30nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314398(US9611249, Compound 29 | {4-[({[5-(2,3-difluorophe...)
Affinity DataIC50: 30nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314374(US9611249, Compound 5 | N-{[1-(2-methoxyethyl)pipe...)
Affinity DataIC50: 50nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314387(US9611249, Compound 15 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 50nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314378(US9611249, Compound 7 | N-{[1-(2-methoxyethyl)pipe...)
Affinity DataIC50: 60nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314377(US9611249, Compound 6 | 5-(2-fluorophenyl)-N-{[1-(...)
Affinity DataIC50: 70nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314396(US9611249, Compound 27 | {4-[({[5-(2,3-dichlorophe...)
Affinity DataIC50: 100nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314397(US9611249, Compound 28 | {4-[({[5-(3-fluorophenyl)...)
Affinity DataIC50: 110nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314381(US9611249, Compound 9 | N-{[1-(2-methoxyethyl)pipe...)
Affinity DataIC50: 200nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314391({4-[({[5-(Pyrimidin-5-yl)-1H-indazol-3- yl]carbony...)
Affinity DataIC50: 220nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314391({4-[({[5-(Pyrimidin-5-yl)-1H-indazol-3- yl]carbony...)
Affinity DataIC50: 530nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314384(US9611249, Compound 12 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 560nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314385(US9611249, Compound 13 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 560nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314388(US9611249, Compound 16 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 580nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314324(US9611249, Compound 1 | [4-({[(5-methoxy-1H-indazo...)
Affinity DataIC50: 670nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314370(US9611249, Compound 3 | [4-({[(5-methoxy-1H-indazo...)
Affinity DataIC50: 690nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314407(US9611249, Compound 38 | N-[(1-{3-[(2E)-but-2-enoy...)
Affinity DataIC50: 780nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314368(US9611249, Compound 2 | 5-methoxy-N-{[1-(2-methoxy...)
Affinity DataIC50: 870nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314409(US9611249, Compound 40 | N-({1-[3-(but-2-ynoylamin...)
Affinity DataIC50: 880nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314383(US9611249, Compound 11 | 5-(4-hydroxyphenyl)-N-{[1...)
Affinity DataIC50: 890nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314395(US9611249, Compound 26 | {4-[({[5-(3,5-Dimethyliso...)
Affinity DataIC50: 910nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314408(US9611249, Compound 39 | 5-methoxy-N-({1-[3-(propa...)
Affinity DataIC50: 950nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314400(US9611249, Compound 31 | [4-({[(5-ethyl-1H-indazol...)
Affinity DataIC50: 960nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314406(US9611249, Compound 37 | N-({1-[3-(butanoylamino)p...)
Affinity DataIC50: 970nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314390(US9611249, Compound 24 | 4-[4-({[(5-methoxy-1H-ind...)
Affinity DataIC50: 1.03E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314402(US9611249, Compound 33 | {4-[({[5-(3,6-dihydro-2H-...)
Affinity DataIC50: 1.04E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314389(US9611249, Compound 18 | 5-(2-ethoxy-4,5-difluorop...)
Affinity DataIC50: 1.06E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314403(US9611249, Compound 34 | [4-({[(5-cyclohexyl-1H-in...)
Affinity DataIC50: 1.07E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314386(US9611249, Compound 14 | N-{[1-(2-methoxyethyl)pip...)
Affinity DataIC50: 1.40E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314404(US9611249, Compound 35 | [4-({[(5-pentyl-1H-indazo...)
Affinity DataIC50: 2.04E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314405(US9611249, Compound 36 | 5-methoxy-N-[(1-{3- [(phe...)
Affinity DataIC50: 3.42E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Angelini Acraf

US Patent
LigandPNGBDBM314401(US9611249, Compound 32 | {4-[({[5-(propan-2-yl)-1H...)
Affinity DataIC50: 3.91E+3nMAssay Description:Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent