Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 1180
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 120nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 150nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 210nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312073(US9603836, Compound 9 | 3-(6-bromo-5-fluoro- 1H-in...)
Affinity DataIC50: 290nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312076(US9603836, Compound 11 | 3-(5-bromo-1H-indol-3- yl...)
Affinity DataIC50: 370nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312084(US9603836, Compound 19 | 3-(6-bromo-1H-indol-3- yl...)
Affinity DataIC50: 420nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312072(US9603836, Compound 7 | 3-(6-chloro-5-fluoro-1H- i...)
Affinity DataIC50: 490nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312074(US9603836, Compound 10 | (R)-3-(6-bromo-5- fluoro-...)
Affinity DataIC50: 620nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312088(US9603836, Compound 24 | 3-(6-fluoronaphthanlen- 1...)
Affinity DataIC50: 1.70E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312086(US9603836, Compound 22 | 3-(2,5-dioxopyrrolidin- 3...)
Affinity DataIC50: 1.70E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312080(US9603836, Compound 15 | 3-(5,6-difluoro-1H- indol...)
Affinity DataIC50: 1.80E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312064(US9603836, Compound 4 | (-)-(R)-3-(1H-indol-3- yl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312069(US9603836, Compound 5 | 3-(5-chloro-1H-indol-3- yl...)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312083(US9603836, Compound 18 | 3-(6-chloro-1H-indol-3- y...)
Affinity DataIC50: 2.10E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312070(US9603836, Compound 6 | (-)-(R)-3-(5-chloro-1H- in...)
Affinity DataIC50: 2.20E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM73346(MLS000099368 | SMR000071516 | cid_363326 | 3-(1H-i...)
Affinity DataIC50: 3.00E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312082(US9603836, Compound 17 | 3-(6-fluoro-1H-indol-3- y...)
Affinity DataIC50: 3.40E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312089(US9603836, Compound 25 | 3-(7-fluoronaphthanlen- 1...)
Affinity DataIC50: 4.60E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312075(US9603836, Compound 10a | US9949951, 10a)
Affinity DataIC50: 8.00E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312079(US9603836, Compound 14 | 3-(2,5-dioxopyrrolidin- 3...)
Affinity DataIC50: 1.20E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312087(US9603836, Compound 23 | 3-(naphthalen-1-yl)- pyrr...)
Affinity DataIC50: 1.80E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312081(US9603836, Compound 16 | 3-(5-fluoro-6-methyl- 1H-...)
Affinity DataIC50: 4.60E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312065(US9603836, Compound 4a | US9949951, 4a)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312071(US9603836, Compound 6a | US9949951, 6a)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312078(US9603836, Compound 13 | 3-(5-methoxy-1H-indol- 3-...)
Affinity DataIC50: 5.30E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312077(US9603836, Compound 12 | 3-(5-methyl-1H-indol-3- y...)
Affinity DataIC50: 5.30E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Iteos Therapeutics

US Patent
LigandPNGBDBM312085(US9603836, Compound 20 | 3-(6-methyl-1H-indol-3- y...)
Affinity DataIC50: 5.40E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent