Compile Data Set for Download or QSAR
Report error Found 339 Enz. Inhib. hit(s) with all data for entry = 222
TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228440(US9556135, 25)
Affinity DataIC50: 0.300nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229582(US9556135, 174)
Affinity DataIC50: 0.330nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230011(US9556135, 178)
Affinity DataIC50: 0.380nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228441(US9556135, 26)
Affinity DataIC50: 0.400nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228479(US9556135, 205)
Affinity DataIC50: 0.440nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230020(US9556135, 203)
Affinity DataIC50: 0.480nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229989(US9556135, 156)
Affinity DataIC50: 0.5nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228404(US9556135, 48)
Affinity DataIC50: 0.540nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230028(US9556135, 216)
Affinity DataIC50: 0.540nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229992(US9556135, 159)
Affinity DataIC50: 0.550nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228414(US9556135, 49)
Affinity DataIC50: 0.560nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229990(US9556135, 157)
Affinity DataIC50: 0.560nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228399(US9556135, 45)
Affinity DataIC50: 0.590nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228473(US9556135, 195)
Affinity DataIC50: 0.590nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228439(US9556135, 24)
Affinity DataIC50: 0.600nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228868(US9556135, 144)
Affinity DataIC50: 0.600nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230018(US9556135, 201)
Affinity DataIC50: 0.620nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230001(US9556135, 192)
Affinity DataIC50: 0.700nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229056(US9556135, 122)
Affinity DataIC50: 0.760nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230025(US9556135, 193)
Affinity DataIC50: 0.760nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230012(US9556135, 179)
Affinity DataIC50: 0.800nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230000(US9556135, 188)
Affinity DataIC50: 0.830nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM50012660(US9273042, 5 | CHEMBL3261078 | US9556135, 19)
Affinity DataIC50: 0.850nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228478(US9556135, 204)
Affinity DataIC50: 0.870nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229508(US9556135, 168)
Affinity DataIC50: 0.920nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230022(US9556135, 207)
Affinity DataIC50: 0.920nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228443(US9556135, 38)
Affinity DataIC50: 1nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228963(US9556135, 125)
Affinity DataIC50: 1nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229982(US9556135, 180)
Affinity DataIC50: 1.10nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228463(US9556135, 116 | BDBM229621 | US9340506, G4B)
Affinity DataIC50: 1.15nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230029(US9556135, 217)
Affinity DataIC50: 1.20nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228869(US9556135, 120)
Affinity DataIC50: 1.30nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229566(US9556135, 162)
Affinity DataIC50: 1.30nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230002(US9556135, 190)
Affinity DataIC50: 1.30nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230017(US9556135, 200)
Affinity DataIC50: 1.30nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228415(US9556135, 70 | US9556135, 69)
Affinity DataIC50: 1.40nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228476(US9556135, 197)
Affinity DataIC50: 1.46nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228437(US9556135, 22)
Affinity DataIC50: 1.5nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230019(US9556135, 202)
Affinity DataIC50: 1.5nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229994(US9556135, 104)
Affinity DataIC50: 1.54nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229049(US9556135, 127)
Affinity DataIC50: 1.60nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229389(US9556135, 131)
Affinity DataIC50: 1.60nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229050(US9556135, 148)
Affinity DataIC50: 1.63nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229051(US9556135, 151)
Affinity DataIC50: 1.70nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM229052(US9556135, 106)
Affinity DataIC50: 1.74nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228474(US9556135, 196)
Affinity DataIC50: 1.81nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228466(US9556135, 117)
Affinity DataIC50: 1.89nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM228401(US9556135, 18)
Affinity DataIC50: 1.90nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230013(US9556135, 199)
Affinity DataIC50: 1.90nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Amgen

US Patent
LigandPNGBDBM230021(US9556135, 206)
Affinity DataIC50: 1.90nMAssay Description:Several animal models, including mouse, rat, dog, and monkey, may be used to screen for inhibition of beta-secretase activity in vivo following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent

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