Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 184
TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204930(1-{2-oxo-2-[(1R,3S,5R)-3-{[1-(trifluoromethyl)-1H-...)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
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TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204926(1-{2-oxo-2-[(1R,3S,5R)-3-{[1-(2,2,2-trifluoroethyl...)
Affinity DataIC50: 64nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204928((1r,3s,5r)-2-(2-(3-acetyl- 1h-pyrazolo[3,4-c]pyrid...)
Affinity DataIC50: 83nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204927(1-(2-oxo-2-((1r,3s,5r)-3-((1- (2,2,2-trifluoroethy...)
Affinity DataIC50: 98nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM204929(1-(2-((1R,3S,5R)-3-(1- isopropyl-1H-pyrazol-3- ylc...)
Affinity DataIC50: 170nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details
Go to US Patent