Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 171
TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200951(US9540352, example 5 | 6-[4-(isoquinolin-1-yloxy)-...)
Affinity DataKi:  1.90nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200985(US9540352, example 11 | 5-[4-(isoquinolin-1-yloxy)...)
Affinity DataKi:  7.80nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200843(US9540352, example 1 | 1,5-dimethyl-6-[2-methyl-4-...)
Affinity DataKi:  28.5nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200931(US9540352, example 3 | (−)-4,6-dimethyl-5-[2...)
Affinity DataKi:  102nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200975(US9540352, example 6 | 8-[4-(4,6-dimethylpyrimidin...)
Affinity DataKi:  105nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200895(US9540352, example 2 | (+)-4,6-dimethyl-5-[2-methy...)
Affinity DataKi:  115nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200976(US9540352, example 7 | 1,5-dimethyl-6-[4-(1,7-naph...)
Affinity DataKi:  119nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200983(US9540352, example 10 | 4,6-dimethyl-5-[2-methyl-4...)
Affinity DataKi:  124nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200977(US9540352, example 8 | 4,6-dimethyl-5-[2-methyl-4-...)
Affinity DataKi:  141nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200988(US9540352, example 12 | 5-{4-[(7-methoxyisoquinoli...)
Affinity DataKi:  186nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200936(US9540352, example 4 | 4,6-dimethyl-5-[4-(1,7-naph...)
Affinity DataKi:  205nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200990(US9540352, example 14 | 1-[4-(3,5-dimethyl-6-oxo-1...)
Affinity DataKi:  261nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200978(US9540352, example 9 | 4,6-dimethyl-5-[2-methyl-4-...)
Affinity DataKi:  306nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
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TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200989(US9540352, example 13 | 1-[4-(3,5-dimethyl-6-oxo-1...)
Affinity DataKi:  334nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
Go to US Patent