Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 8555
TargetPlasminogen(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM200012(US9234000, 3 | US9512065, N-[(R)-1-[(S)-1-(4-amino...)
Affinity DataIC50: 3.50E+3nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetCoagulation factor X(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM200012(US9234000, 3 | US9512065, N-[(R)-1-[(S)-1-(4-amino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetCoagulation factor XII [20-615](Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM200012(US9234000, 3 | US9512065, N-[(R)-1-[(S)-1-(4-amino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetSerine protease 1(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM200012(US9234000, 3 | US9512065, N-[(R)-1-[(S)-1-(4-amino...)
Affinity DataIC50: 1.08E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetProthrombin(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM200012(US9234000, 3 | US9512065, N-[(R)-1-[(S)-1-(4-amino...)
Affinity DataIC50: 4.00E+4nMAssay Description:Human serine protease enzymes plasmin, thrombin, trypsin, Factor Xa and Factor XIIa were assayed for enzymatic activity using an appropriate fluoroge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent