Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 8521
TargetTyrosine-protein kinase Lck(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  4.20nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  2.80nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataKd:  7.10nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of the compound of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that des...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataIC50: 11nMAssay Description:Method 2: This method follows the same steps as Method 1 below, but utilises a higher concentration of the p38 MAPKα protein (2.5 uL of 200 ng/...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activities of the compound of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that des...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM255476(US9499486, 1 | US10125100, Example 1 | US9751837, ...)
Affinity DataIC50: 115nMAssay Description:Method 2: This method follows the same steps as Method 1 above, but utilises a shorter period of mixing of the test compound (105 minutes instead of ...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2017
Entry Details
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