Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 8488
TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090760(US9480684, 30, R = Ph- BU10119 | CHEMBL3581750 | U...)
Affinity DataKi:  0.0400nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090731(US9480684, 22, R = 3- MePh- BU10112 | CHEMBL358174...)
Affinity DataKi:  0.0400nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090755(US9480684, 22, R = 4- FPh- BU10120 | CHEMBL3581743...)
Affinity DataKi:  0.0500nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090694(US9480684, 22, R = Ph- BU128 | CHEMBL3581740 | US9...)
Affinity DataKi:  0.0800nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090694(US9480684, 22, R = Ph- BU128 | CHEMBL3581740 | US9...)
Affinity DataKi:  0.0800nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015009(CHEMBL3262367 | US9480684, 7a, R = 3,5- diMePh- BU...)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090760(US9480684, 30, R = Ph- BU10119 | CHEMBL3581750 | U...)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015011(CHEMBL3262363 | US9480684, 7a, 2- MePh- BU10101 | ...)
Affinity DataKi:  0.160nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090755(US9480684, 22, R = 4- FPh- BU10120 | CHEMBL3581743...)
Affinity DataKi:  0.160nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090731(US9480684, 22, R = 3- MePh- BU10112 | CHEMBL358174...)
Affinity DataKi:  0.170nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015011(CHEMBL3262363 | US9480684, 7a, 2- MePh- BU10101 | ...)
Affinity DataKi:  0.190nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
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Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090760(US9480684, 30, R = Ph- BU10119 | CHEMBL3581750 | U...)
Affinity DataKi:  0.25nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015009(CHEMBL3262367 | US9480684, 7a, R = 3,5- diMePh- BU...)
Affinity DataKi:  0.280nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090731(US9480684, 22, R = 3- MePh- BU10112 | CHEMBL358174...)
Affinity DataKi:  0.400nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090755(US9480684, 22, R = 4- FPh- BU10120 | CHEMBL3581743...)
Affinity DataKi:  0.470nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50090694(US9480684, 22, R = Ph- BU128 | CHEMBL3581740 | US9...)
Affinity DataKi:  0.480nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015003(CHEMBL3262089 | US9480684, 7a, R = Ph- BU127 | US9...)
Affinity DataKi:  0.490nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015004(CHEMBL3262372 | US9480684, 7a, R = 2- thienyl- BU0...)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM206331(US9480684, 23, R = Ph- BU129 | US9259422, 23, R = ...)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015003(CHEMBL3262089 | US9480684, 7a, R = Ph- BU127 | US9...)
Affinity DataKi:  0.710nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM206331(US9480684, 23, R = Ph- BU129 | US9259422, 23, R = ...)
Affinity DataKi:  1.08nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50014995(CHEMBL3262090 | US9480684, 13a, R = Ph- BU126 | US...)
Affinity DataKi:  1.25nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015003(CHEMBL3262089 | US9480684, 7a, R = Ph- BU127 | US9...)
Affinity DataKi:  1.91nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50014995(CHEMBL3262090 | US9480684, 13a, R = Ph- BU126 | US...)
Affinity DataKi:  2.55nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM206331(US9480684, 23, R = Ph- BU129 | US9259422, 23, R = ...)
Affinity DataKi:  3.02nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetDelta-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015005(CHEMBL3262093 | US9480684, 13b, R = Ph- BU125 | US...)
Affinity DataKi:  3.21nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015005(CHEMBL3262093 | US9480684, 13b, R = Ph- BU125 | US...)
Affinity DataKi:  3.84nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetMu-type opioid receptor(Rat)
The University of Bath

US Patent
LigandPNGBDBM50015005(CHEMBL3262093 | US9480684, 13b, R = Ph- BU125 | US...)
Affinity DataKi:  4.03nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetKappa-type opioid receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50014995(CHEMBL3262090 | US9480684, 13a, R = Ph- BU126 | US...)
Affinity DataKi:  4.40nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090755(US9480684, 22, R = 4- FPh- BU10120 | CHEMBL3581743...)
Affinity DataKi:  34nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015004(CHEMBL3262372 | US9480684, 7a, R = 2- thienyl- BU0...)
Affinity DataKi:  34.5nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50015003(CHEMBL3262089 | US9480684, 7a, R = Ph- BU127 | US9...)
Affinity DataKi:  43.2nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090731(US9480684, 22, R = 3- MePh- BU10112 | CHEMBL358174...)
Affinity DataKi:  79nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090760(US9480684, 30, R = Ph- BU10119 | CHEMBL3581750 | U...)
Affinity DataKi:  80nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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TargetNociceptin receptor(Human)
The University of Bath

US Patent
LigandPNGBDBM50090694(US9480684, 22, R = Ph- BU128 | CHEMBL3581740 | US9...)
Affinity DataKi:  97nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
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