Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 8453
TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50: 2.90nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 3.70nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50: 108nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50: 117nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50: 671nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50: 703nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50: 833nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50: 870nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 961nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 982nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50: 1.04E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50: 1.82E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50: 4.38E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50: 6.20E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
Go to US Patent