Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8277
TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239006(US9403846, 20)
Affinity DataIC50: 116nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239005(US9403846, 19)
Affinity DataIC50: 184nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238993(US9403846, 8)
Affinity DataIC50: 235nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238984(US9403846, 2)
Affinity DataIC50: 281nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239007(US9403846, 21)
Affinity DataIC50: 302nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238986(US9403846, 3)
Affinity DataIC50: 337nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238989(US9403846, 6)
Affinity DataIC50: 346nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238998(US9403846, 12)
Affinity DataIC50: 395nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238999(US9403846, 13)
Affinity DataIC50: 422nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238983(US9403846, 1)
Affinity DataIC50: 447nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238991(US9403846, 7)
Affinity DataIC50: 484nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238996(US9403846, 10)
Affinity DataIC50: 572nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239001(US9403846, 15)
Affinity DataIC50: 715nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239002(US9403846, 16)
Affinity DataIC50: 897nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238995(US9403846, 9)
Affinity DataIC50: 1.05E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239000(US9403846, 14)
Affinity DataIC50: 1.28E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 2 [21-466](Human)
Pfizer

US Patent
LigandPNGBDBM238983(US9403846, 1)
Affinity DataIC50: 1.29E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic substrate that can be cleaved by BACE2 having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Green at the Cy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238987(US9403846, 4)
Affinity DataIC50: 1.31E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238988(US9403846, 5)
Affinity DataIC50: 1.41E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238997(US9403846, 11)
Affinity DataIC50: 1.42E+3nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 2 [21-466](Human)
Pfizer

US Patent
LigandPNGBDBM238984(US9403846, 2)
Affinity DataIC50: 2.26E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic substrate that can be cleaved by BACE2 having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Green at the Cy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 2 [21-466](Human)
Pfizer

US Patent
LigandPNGBDBM238986(US9403846, 3)
Affinity DataIC50: 2.49E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic substrate that can be cleaved by BACE2 having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Green at the Cy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239004(US9403846, 18)
Affinity DataIC50: 1.56E+4nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM239003(US9403846, 17)
Affinity DataIC50: 2.57E+4nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238990(US9403846, C48)
Affinity DataIC50: 1.00E+5nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238985(US9403846, C23)
Affinity DataIC50: 1.00E+5nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238994(US9403846, C74)
Affinity DataIC50: 8.60E+7nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238992(US9403846, C61)
Affinity DataIC50: 3.70E+7nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent