Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8045
TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155568(US9012475, 12 | US9346787, 12 | US10092556, Exampl...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155569(US9012475, 13 | US9346787, 13 | US10092556, Exampl...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155565(US9012475, 1 | US9346787, 1 | US10092556, Example ...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155566(US9012475, 2 | US9346787, 2 | US10092556, Example ...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155574(US9012475, 24 | US9346787, 24 | US10092556, Exampl...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155567(US9012475, 11 | US9346787, 11 | US10092556, Exampl...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50277545(Alisertib | MLN8237 | CHEMBL483158 | 4-(9-chloro-7...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155573(US9012475, 22 | US9346787, 22 | US10092556, Exampl...)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155575(US9012475, 28 | US9346787, 28 | US10092556, Exampl...)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155576(US9012475, 29 | US9346787, 29 | US10092556, Exampl...)
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155570(US9012475, 14 | US9346787, 14 | US10092556, Exampl...)
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US9012475, 17 | US9346787, 17 | US10092556, Exampl...)
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155572(US9012475, 19 | US9346787, 19 | US10092556, Exampl...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM50277545(Alisertib | MLN8237 | CHEMBL483158 | 4-(9-chloro-7...)
Affinity DataIC50: 90nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155565(US9012475, 1 | US9346787, 1 | US10092556, Example ...)
Affinity DataIC50: 140nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155569(US9012475, 13 | US9346787, 13 | US10092556, Exampl...)
Affinity DataIC50: 180nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155574(US9012475, 24 | US9346787, 24 | US10092556, Exampl...)
Affinity DataIC50: 190nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
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TargetAurora kinase A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM231252(US9346787, Comparative Example 6 | US10092556, Com...)
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155568(US9012475, 12 | US9346787, 12 | US10092556, Exampl...)
Affinity DataIC50: 260nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM231252(US9346787, Comparative Example 6 | US10092556, Com...)
Affinity DataIC50: 320nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155566(US9012475, 2 | US9346787, 2 | US10092556, Example ...)
Affinity DataIC50: 340nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155573(US9012475, 22 | US9346787, 22 | US10092556, Exampl...)
Affinity DataIC50: 380nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155576(US9012475, 29 | US9346787, 29 | US10092556, Exampl...)
Affinity DataIC50: 390nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155575(US9012475, 28 | US9346787, 28 | US10092556, Exampl...)
Affinity DataIC50: 450nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155570(US9012475, 14 | US9346787, 14 | US10092556, Exampl...)
Affinity DataIC50: 460nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155572(US9012475, 19 | US9346787, 19 | US10092556, Exampl...)
Affinity DataIC50: 680nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US9012475, 17 | US9346787, 17 | US10092556, Exampl...)
Affinity DataIC50: 900nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155567(US9012475, 11 | US9346787, 11 | US10092556, Exampl...)
Affinity DataIC50: 930nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent